Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 9/20 | 0.44 |
| ▸ | MEN1 | O00255 | 7/20 | 0.44 |
| ▸ | USP2 | O75604 | 6/20 | 0.44 |
| ▸ | KEAP1 | Q14145 | 3/20 | 0.44 |
| ▸ | NFE2L2 | Q16236 | 3/20 | 0.44 |
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | HTT | P42858 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 4/20 | 0.43 |
| ▸ | RECQL | P46063 | 2/20 | 0.43 |
| ▸ | CASP6 | P55212 | 2/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.43 |
| ▸ | APEX1 | P27695 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11209931 | 0.91 | KMT2A (0.44) | KMT2AMEN1USP2KEAP1NFE2L2 | |
| SCHEMBL11206466 | 0.91 | KMT2A (0.41) | KMT2AMEN1USP2KEAP1NFE2L2 | |
| SCHEMBL11204757 | 0.82 | KMT2A (0.44) | KMT2AMEN1USP2KEAP1NFE2L2 | |
| SCHEMBL11211251 | 0.81 | HPGD (0.59) | KMT2AMEN1KDM4EALDH1A1HTT | |
| SCHEMBL6521460 | 0.78 | MCL1 (0.38) | KMT2AMEN1ALDH1A1MAPTHTT | |
| SCHEMBL11210954 | 0.77 | KMT2A (0.40) | KMT2AMEN1KDM4EALDH1A1MAPT | |
| SCHEMBL3288014 | 0.76 | MCL1 (0.53) | KMT2AMEN1USP2KEAP1NFE2L2 | |
| SCHEMBL28533652 | 0.76 | KMT2A (0.51) | KMT2AMEN1USP2KEAP1NFE2L2 | |
| SCHEMBL20735077 | 0.74 | PRMT1 (0.72) | KMT2AMEN1USP2KEAP1NFE2L2 | |
| SCHEMBL14003750 | 0.74 | ANPEP (0.42) | KMT2AMEN1USP2KEAP1NFE2L2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4417039-A | Cis-enyne aromatic and aromatic heterocyclic polymers | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE AIR FORCE (US) | 1983-11-22 | — | — | US | disclosed |