Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 11/20 | 0.44 |
| ▸ | MEN1 | O00255 | 9/20 | 0.44 |
| ▸ | USP2 | O75604 | 7/20 | 0.44 |
| ▸ | KEAP1 | Q14145 | 5/20 | 0.44 |
| ▸ | NFE2L2 | Q16236 | 5/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.43 |
| ▸ | NPC1 | O15118 | 3/20 | 0.43 |
| ▸ | TLR9 | Q9NR96 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.41 |
| ▸ | HTT | P42858 | 4/20 | 0.41 |
| ▸ | MAPT | P10636 | 4/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
| ▸ | CASP6 | P55212 | 1/20 | 0.40 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11209931 | 0.92 | KMT2A (0.44) | KMT2AMEN1USP2KEAP1NFE2L2 | |
| SCHEMBL11206466 | 0.92 | KMT2A (0.41) | KMT2AMEN1USP2KEAP1NFE2L2 | |
| SCHEMBL11216136 | 0.82 | ALDH1A1 (0.54) | KMT2AMEN1ALDH1A1KDM4EMAPT | |
| SCHEMBL11210959 | 0.82 | KMT2A (0.44) | KMT2AMEN1USP2KEAP1NFE2L2 | |
| SCHEMBL11558315 | 0.82 | TYMS (0.42) | KMT2AMEN1ALDH1A1KDM4EHTT | |
| SCHEMBL11204754 | 0.81 | KMT2A (0.38) | KMT2AMEN1USP2ALDH1A1HTT | |
| SCHEMBL11201186 | 0.81 | BRD4 (0.56) | KMT2AMEN1NPC1ALDH1A1HTT | |
| SCHEMBL22627212 | 0.78 | NPC1 (0.53) | KMT2AMEN1USP2KEAP1NFE2L2 | |
| SCHEMBL22580621 | 0.77 | ALDH1A1 (0.54) | KMT2AMEN1ALDH1A1KDM4EHTT | |
| SCHEMBL11200203 | 0.76 | MEN1 (0.62) | KMT2AMEN1USP2KEAP1NFE2L2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4417039-A | Cis-enyne aromatic and aromatic heterocyclic polymers | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE AIR FORCE (US) | 1983-11-22 | — | — | US | disclosed |
| US-4380619-A | POLYBENZOTHIAZOLES; N-HETEROCYCLIC POLYMERS; SOLUBILITY; HEAT RESISTANCE; AIRCRAFT; AEROSPACE | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE AIR FORCE (US) | 1983-04-19 | — | — | US | disclosed |