Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCL1 | Q07820 | 6/20 | 0.53 |
| ▸ | BCL2 | P10415 | 5/20 | 0.53 |
| ▸ | BCL2L1 | Q07817 | 4/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 8/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.51 |
| ▸ | USP2 | O75604 | 4/20 | 0.51 |
| ▸ | MEN1 | O00255 | 4/20 | 0.51 |
| ▸ | MAPT | P10636 | 3/20 | 0.51 |
| ▸ | HTT | P42858 | 3/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.51 |
| ▸ | KEAP1 | Q14145 | 2/20 | 0.51 |
| ▸ | NFE2L2 | Q16236 | 2/20 | 0.51 |
| ▸ | POLB | P06746 | 2/20 | 0.49 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.49 |
| ▸ | RECQL | P46063 | 1/20 | 0.49 |
| ▸ | CASP6 | P55212 | 1/20 | 0.49 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3284746 | 0.85 | MCL1 (0.52) | MCL1BCL2BCL2L1KMT2AKDM4E | |
| SCHEMBL28533652 | 0.84 | KMT2A (0.51) | MCL1BCL2KMT2AKDM4EALDH1A1 | |
| SCHEMBL14935514 | 0.82 | MCL1 (0.60) | MCL1BCL2BCL2L1KMT2AKDM4E | |
| SCHEMBL3285110 | 0.80 | MCL1 (0.56) | MCL1BCL2KMT2AKDM4EALDH1A1 | |
| SCHEMBL14003750 | 0.79 | ANPEP (0.42) | MCL1BCL2BCL2L1KMT2AKDM4E | |
| SCHEMBL17948241 | 0.79 | PRMT1 (0.68) | KMT2AKDM4EALDH1A1USP2MEN1 | |
| SCHEMBL14003757 | 0.77 | ANPEP (0.56) | MCL1BCL2BCL2L1KMT2AKDM4E | |
| SCHEMBL11210959 | 0.76 | KMT2A (0.44) | MCL1BCL2KMT2AKDM4EALDH1A1 | |
| SCHEMBL3284775 | 0.76 | MCL1 (0.46) | MCL1BCL2BCL2L1KMT2AKDM4E | |
| SCHEMBL14003739 | 0.76 | ANPEP (0.45) | MCL1BCL2BCL2L1KMT2AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7714044-B2 | Use of 4-cyano-naphthalene-1, 8-dicarboximide derivatives and related compounds to protect organic material from the damaging effects of light | BASF AKITENGESELLSCHAFT (DE) | 2010-05-11 | — | — | US | disclosed |
| US-20070100033-A1 | Use of 4-cyano-naphthalene-1, 8-dicarboximide derivatives and related compounds to protect organic material from the damaging effects of light | BAST AKTIENGESELLSCHAFT (DE) | 2007-05-03 | — | — | US | disclosed |
| US-20050171252-A1 | Use of naphthalin-1,8-dicarboxylic acid monoimides | BASF AKTIENGESELLSCHAFT (DE) | 2005-08-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050171252-A1 | Use of naphthalin-1,8-dicarboxylic acid monoimides | NDC1, NDUFC1, NDUFC2 | MCL1 2655/4885BCL2 1238/4885BCL2L1 763/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.