Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 4/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.46 |
| ▸ | MEN1 | O00255 | 4/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 3/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | IDH1 | O75874 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10959984 | 0.82 | CYP19A1 (0.56) | CYP19A1KMT2AMEN1ALDH1A1HSP90AA1 | |
| SCHEMBL28026657 | 0.81 | KMT2A (0.46) | CYP19A1KMT2AMEN1ALDH1A1LMNA | |
| SCHEMBL7789025 | 0.81 | KMT2A (0.48) | KMT2AMEN1ALDH1A1POLBHPGD | |
| SCHEMBL12462114 | 0.79 | CYP19A1 (0.53) | CYP19A1KMT2AMEN1ALDH1A1HSP90AA1 | |
| SCHEMBL5544140 | 0.78 | TSHR (0.58) | CYP19A1KMT2AMEN1ALDH1A1HSP90AA1 | |
| SCHEMBL7783933 | 0.78 | TSHR (0.58) | CYP19A1KMT2AMEN1ALDH1A1HSP90AA1 | |
| SCHEMBL11127036 | 0.78 | CYP19A1 (0.56) | CYP19A1KMT2AMEN1ALDH1A1HSP90AA1 | |
| SCHEMBL12309934 | 0.78 | KMT2A (0.54) | CYP19A1KMT2AMEN1ALDH1A1HSP90AA1 | |
| SCHEMBL10926146 | 0.78 | CYP19A1 (0.51) | CYP19A1KMT2AMEN1ALDH1A1HSP90AA1 | |
| SCHEMBL11182304 | 0.77 | CYP19A1 (0.41) | CYP19A1KMT2AMEN1ALDH1A1HSP90AA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4327104-A | FUNGICIDES AND BACTERICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 1982-04-27 | — | — | US | claimed |
| US-4400388-A | Fungicidal 1-phenyl-2-(1,2,4-triazol-1-yl)-ethyl ethers | BAYER AKTIENGESELLSCHAFT (DE) | 1983-08-23 | — | — | US | disclosed |
| US-4400388-A | Fungicidal 1-phenyl-2-(1,2,4-triazol-1-yl)-ethyl ethers | BAYER AKTIENGESELLSCHAFT (DE) | 1983-08-23 | — | — | US | disclosed |
| US-4400388-A | Fungicidal 1-phenyl-2-(1,2,4-triazol-1-yl)-ethyl ethers | BAYER AKTIENGESELLSCHAFT (DE) | 1983-08-23 | — | — | US | disclosed |
| US-4327104-A | FUNGICIDES AND BACTERICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 1982-04-27 | — | — | US | disclosed |
| US-4327104-A | FUNGICIDES AND BACTERICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 1982-04-27 | — | — | US | disclosed |