Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.58 |
| ▸ | CYP19A1 | P11511 | 4/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.50 |
| ▸ | MEN1 | O00255 | 3/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7783933 | 1.00 | TSHR (0.58) | TSHRCYP19A1KMT2AMEN1ALDH1A1 | |
| SCHEMBL10999589 | 0.91 | MEN1 (0.49) | TSHRCYP19A1KMT2AMEN1ALDH1A1 | |
| SCHEMBL11197512 | 0.87 | KDM4E (0.50) | TSHRCYP19A1KMT2AMEN1ALDH1A1 | |
| SCHEMBL10959984 | 0.84 | CYP19A1 (0.56) | CYP19A1KMT2AMEN1ALDH1A1HSP90AA1 | |
| SCHEMBL11270600 | 0.83 | NPSR1 (0.49) | TSHRCYP19A1KMT2AMEN1ALDH1A1 | |
| SCHEMBL11273790 | 0.83 | CYP19A1 (0.59) | TSHRCYP19A1KMT2AHSP90AA1POLB | |
| SCHEMBL11188697 | 0.83 | HMOX1 (0.51) | TSHRCYP19A1KMT2AMEN1ALDH1A1 | |
| SCHEMBL9634892 | 0.83 | CYP19A1 (0.50) | CYP19A1KMT2AMEN1ALDH1A1POLB | |
| SCHEMBL11001193 | 0.82 | CYP19A1 (0.56) | CYP19A1KMT2AMEN1ALDH1A1HSP90AA1 | |
| SCHEMBL11182572 | 0.82 | POLB (0.42) | TSHRCYP19A1KMT2AMEN1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 28 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1035357-C | Pharmaceutical preparations | MACK CHEM PHARM (DE) | 1997-07-09 | — | — | CN | claimed |
| CN-1052046-A | pharmaceutical preparation | MACK CHEM PHARM (DE) | 1991-06-12 | — | — | CN | claimed |
| CN-110603032-A | Strippable nail paint | 牡蛎壳公司 | 2019-12-20 | — | — | CN | disclosed |
| CN-110582261-A | Colored cuticle separating nail lacquer | 牡蛎壳公司 | 2019-12-17 | — | — | CN | disclosed |
| US-20180194742-A1 | Antifungal Compounds | UNIVERSITY OF KENTUCKY RESEARCH FOUNDATION | 2018-07-12 | — | — | US | disclosed |
| US-8975289-B2 | Benzyl aralkyl ether compounds, method for preparing same, intermediate compounds, use of said compounds, method for treatment and/or prevention, pharmaceutical composition and medicament containing same | Biolab Sanus Farmaceutical Ltda. (BR) | 2015-03-10 | — | — | US | disclosed |
| US-8975289-B2 | Benzyl aralkyl ether compounds, method for preparing same, intermediate compounds, use of said compounds, method for treatment and/or prevention, pharmaceutical composition and medicament containing same | Biolab Sanus Farmaceutical Ltda. (BR) | 2015-03-10 | — | — | US | disclosed |
| US-20120196908-A1 | BENZYL ARALKYL ETHER COMPOUNDS, METHOD FOR PREPARING SAME, INTERMEDIATE COMPOUNDS, USE OF SAID COMPOUNDS, METHOD FOR TREATMENT AND/OR PREVENTION, PHARMACEUTICAL COMPOSITION AND MEDICAMENT CONTAINING SAME | BIOLAB SANUS FARMACEUTICA LTDA. (BR) | 2012-08-02 | — | — | US | disclosed |
| US-20120196908-A1 | BENZYL ARALKYL ETHER COMPOUNDS, METHOD FOR PREPARING SAME, INTERMEDIATE COMPOUNDS, USE OF SAID COMPOUNDS, METHOD FOR TREATMENT AND/OR PREVENTION, PHARMACEUTICAL COMPOSITION AND MEDICAMENT CONTAINING SAME | BIOLAB SANUS FARMACEUTICA LTDA. (BR) | 2012-08-02 | — | — | US | disclosed |
| EP-2471781-A1 | BENZYL ARALKYL ETHER COMPOUNDS, METHOD FOR PREPARING SAME, INTERMEDIATE COMPOUNDS, USE OF SAID COMPOUNDS, METHOD FOR TREATMENT AND/OR PREVENTION, PHARMACEUTICAL COMPOSITION AND MEDICAMENT CONTAINING SAME | Biolab Sanus Farmacéutica Ltda (BR) | 2012-07-04 | — | — | EP | disclosed |
| EP-1827400-A2 | TOPICAL SKIN PATCH CONTAINING XANTHOPHYLLS | Nu-Tein Co., Inc. (US) | 2007-09-05 | — | — | EP | disclosed |
| US-4400388-A | Fungicidal 1-phenyl-2-(1,2,4-triazol-1-yl)-ethyl ethers | BAYER AKTIENGESELLSCHAFT (DE) | 1983-08-23 | — | — | US | disclosed |
| EP-0068144-A1 | 1,1-Diphenyl-2-triazolyl-ethanes, their preparation and their application as fungicides | HOECHST AKTIENGESELLSCHAFT (DE) | 1983-01-05 | — | — | EP | disclosed |
| US-4349556-A | Pesticidally active 1-acyloxy-1-phenyl-2-azolyl-ethanes | BAYER AKTIENGESELLSCHAFT (DE) | 1982-09-14 | — | — | US | disclosed |
| US-4327104-A | FUNGICIDES AND BACTERICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 1982-04-27 | — | — | US | disclosed |
| US-4315017-A | Triazole derivatives | BASF AKTIENGESELLSCHAFT (DE) | 1982-02-09 | — | — | US | disclosed |
| EP-0008651-B1 | DERIVATIVES OF TRIAZOLE, PROCESS FOR THEIR PRODUCTION AND INSECTICIDES CONTAINING THEM | BASF Aktiengesellschaft (DE) | 1981-10-14 | — | — | EP | disclosed |
| US-4256754-A | PHENYL-1,2,4-TRIAZOLE DERIVATIVE, CARBAMATE | BASF AKTIENGESELLSCHAFT (DE) | 1981-03-17 | — | — | US | disclosed |
| EP-0008651-A1 | Derivatives of triazole, process for their production and insecticides containing them | BASF Aktiengesellschaft (DE) | 1980-03-19 | — | — | EP | disclosed |
| US-4102891-A | FUNGICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 1978-07-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180194742-A1 | Antifungal Compounds | ERG28, DPM1, CYP51A1 | TSHR 4849/4885CYP19A1 2297/4885KMT2A 4101/4885 |
| US-20120196908-A1 | BENZYL ARALKYL ETHER COMPOUNDS, METHOD FOR PREPARING SAME, INTERMEDIATE COMPOUNDS, USE OF SAID COMPOUNDS, METHOD FOR TREATMENT AND/OR PREVENTION, PHARMACEUTICAL COMPOSITION AND MEDICAMENT CONTAINING SAME | CYP2E1, CYP1A1, CYP2S1 | TSHR 888/4885CYP19A1 166/4885KMT2A 2661/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.