Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.58 |
| ▸ | CYP19A1 | P11511 | 4/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.50 |
| ▸ | MEN1 | O00255 | 3/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5544140 | 1.00 | TSHR (0.58) | TSHRCYP19A1KMT2AMEN1ALDH1A1 | |
| SCHEMBL10999589 | 0.91 | MEN1 (0.49) | TSHRCYP19A1KMT2AMEN1ALDH1A1 | |
| SCHEMBL11197512 | 0.87 | KDM4E (0.50) | TSHRCYP19A1KMT2AMEN1ALDH1A1 | |
| SCHEMBL10959984 | 0.84 | CYP19A1 (0.56) | CYP19A1KMT2AMEN1ALDH1A1HSP90AA1 | |
| SCHEMBL11270600 | 0.83 | NPSR1 (0.49) | TSHRCYP19A1KMT2AMEN1ALDH1A1 | |
| SCHEMBL11273790 | 0.83 | CYP19A1 (0.59) | TSHRCYP19A1KMT2AHSP90AA1POLB | |
| SCHEMBL11188697 | 0.83 | HMOX1 (0.51) | TSHRCYP19A1KMT2AMEN1ALDH1A1 | |
| SCHEMBL9634892 | 0.83 | CYP19A1 (0.50) | CYP19A1KMT2AMEN1ALDH1A1POLB | |
| SCHEMBL11001193 | 0.82 | CYP19A1 (0.56) | CYP19A1KMT2AMEN1ALDH1A1HSP90AA1 | |
| SCHEMBL11182572 | 0.82 | POLB (0.42) | TSHRCYP19A1KMT2AMEN1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9434970-B2 | Method for preparation of carbamic acid (R)-1-aryl-2-tetrazolyl-ethyl ester | SK BIOPHARMACEUTICALS CO., LTD. (KR) | 2016-09-06 | — | — | US | disclosed |
| US-20150252398-A1 | METHOD FOR PREPARATION OF CARBAMIC ACID (R)-1-ARYL-2-TETRAZOLYL-ETHYL ESTER | SK BIOPHARMACEUTICALS CO LTD (KR) | 2015-09-10 | — | — | US | disclosed |
| US-9068207-B2 | Method for preparation of carbamic acid (R)-1-aryl-2-tetrazolyl-ethyl ester | SK BIOPHARMACEUTICALS CO. LTD. (KR) | 2015-06-30 | — | — | US | disclosed |
| US-20140073018-A1 | Method for Preparation of Carbamic Acid (R)-1-Aryl-2 Tetrazolyl-Ethyl Ester | SK BIOPHARMACEUTICALS CO. LTD. (KR) | 2014-03-13 | — | — | US | disclosed |
| US-8501436-B2 | Method for preparation of carbamic acid (R)-1-aryl-2-tetrazolyl-ethyl ester | SK BIOPHARMACEUTICALS CO. LTD. (KR) | 2013-08-06 | — | — | US | disclosed |
| US-8404461-B2 | Method for preparation of carbamic acid (R)-1-aryl-2-tetrazolyl-ethyl ester | SK Biopharmaceutical Co. Ltd. (KR) | 2013-03-26 | — | — | US | disclosed |
| US-20110111467-A1 | Method for Preparation of Carbamic Acid (R)-1-Aryl-2-Tetrazolyl-Ethyl Ester | SK BIOPHARMACEUTICALS CO. LTD. (KR) | 2011-05-12 | — | — | US | disclosed |
| US-20100323410-A1 | METHOD FOR PREPARATION OF CARBAMIC ACID (R)-1-ARYL-2-TETRAZOLYL-ETHYL ESTER | SK BIOPHARMACEUTICALS CO. LTD. (KR) | 2010-12-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110111467-A1 | Method for Preparation of Carbamic Acid (R)-1-Aryl-2-Tetrazolyl-Ethyl Ester | CES1, ADH1A, ADH1C | TSHR 460/4885CYP19A1 333/4885KMT2A 622/4885 |
| US-20100323410-A1 | METHOD FOR PREPARATION OF CARBAMIC ACID (R)-1-ARYL-2-TETRAZOLYL-ETHYL ESTER | CPS1, ADH1A, KHK | TSHR 557/4885CYP19A1 536/4885KMT2A 554/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.