Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 6/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.55 |
| ▸ | MAPT | P10636 | 2/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.52 |
| ▸ | NPC1 | O15118 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.52 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.52 |
| ▸ | RAB9A | P51151 | 1/20 | 0.52 |
| ▸ | GFER | P55789 | 1/20 | 0.52 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.52 |
| ▸ | RELA | Q04206 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.52 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.52 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.52 |
| ▸ | RECQL | P46063 | 1/20 | 0.48 |
| ▸ | BLM | P54132 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | FTO | Q9C0B1 | 9/20 | 0.48 |
| ▸ | TTR | P02766 | 3/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11346216 | 0.84 | MEN1 (0.71) | MEN1KMT2AMAPTKDM4ENPC1 | |
| SCHEMBL9299014 | 0.81 | KEAP1 (0.51) | MEN1KMT2ANPC1ALDH1A1RAB9A | |
| SCHEMBL9299009 | 0.81 | KEAP1 (0.51) | MEN1KMT2ANPC1ALDH1A1RAB9A | |
| SCHEMBL11493912 | 0.78 | MEN1 (0.51) | MEN1KMT2AMAPTKDM4ENPC1 | |
| SCHEMBL11203574 | 0.78 | KMT2A (0.51) | MEN1KMT2AKDM4ENPC1ALDH1A1 | |
| SCHEMBL11205022 | 0.77 | MEN1 (0.53) | MEN1KMT2AMAPTKDM4ENPC1 | |
| SCHEMBL7584703 | 0.73 | NPC1 (0.53) | MEN1KMT2AMAPTKDM4ENPC1 | |
| SCHEMBL6244215 | 0.72 | KCNQ2 (0.53) | MEN1KMT2AMAPTKDM4ENPC1 | |
| SCHEMBL10385663 | 0.72 | MEN1 (0.72) | MEN1KMT2AMAPTKDM4ENPC1 | |
| SCHEMBL7577574 | 0.71 | MEN1 (0.48) | MEN1KMT2AALDH1A1RAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0006713-B1 | NOVEL ALPHA-AMINO-PHENYLACETIC ACID DERIVATIVES, PROCESSES FOR THEIR PREPARATION, THEIR USE AS HERBICIDAL, ALGICIDAL AND PLANT GROWTH REGULATING AGENTS, AND HERBICIDAL, ALGICIDAL AND PLANT GROWTH REGULATING COMPOSITIONS CONTAINING THEM | JANSSEN PHARMACEUTICA N.V. (BE) | 1983-07-13 | — | — | EP | disclosed |
| US-4246429-A | HERBICIDES, ALGICIDES, PLANT GROWTH REGULATORS | JANSSEN PHARMACEUTICA, N.V. (BE) | 1981-01-20 | — | — | US | disclosed |
| EP-0006713-A1 | Novel alpha-amino-phenylacetic acid derivatives, processes for their preparation, their use as herbicidal, algicidal and plant growth regulating agents, and herbicidal, algicidal and plant growth regulating compositions containing them | JANSSEN PHARMACEUTICA N.V. (BE) | 1980-01-09 | — | — | EP | disclosed |