SCHEMBL11211240

SCHEMBL11211240

O=C1C(Cl)=C(Cl)C(=O)N1c1ccccc1Cl

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MGLL Q99685 1/20 0.63
ALDH1A1 P00352 5/20 0.62
MAPT P10636 5/20 0.62
POLB P06746 3/20 0.62
HSD17B10 Q99714 3/20 0.62
TSHR P16473 3/20 0.62
L3MBTL1 Q9Y468 2/20 0.62
ALOX15 P16050 1/20 0.62
CASP1 P29466 1/20 0.62
MEN1 O00255 2/20 0.59
KMT2A Q03164 2/20 0.59
RAD51 Q06609 2/20 0.58
BCL2A1 Q16548 1/20 0.58
PKM P14618 1/20 0.58
PGR P06401 1/20 0.49
CYP3A4 P08684 1/20 0.46
NFKB1 P19838 1/20 0.46
PMP22 Q01453 1/20 0.46
KDM4E B2RXH2 1/20 0.44
USP2 O75604 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2549717 0.84 MEN1 (0.73) MGLLALDH1A1MAPTPOLBHSD17B10
SCHEMBL15437834 0.83 RAD51 (0.60) MGLLALDH1A1MAPTPOLBHSD17B10
SCHEMBL15758488 0.83 RAD51 (0.60) MGLLALDH1A1MAPTPOLBHSD17B10
SCHEMBL11608927 0.79 RECQL (0.50) ALDH1A1MAPTPOLBHSD17B10TSHR
SCHEMBL29644716 0.79 MGLL (0.55) MGLLALDH1A1MAPTPOLBHSD17B10
SCHEMBL15437831 0.79 MGLL (0.55) MGLLALDH1A1MAPTPOLBHSD17B10
SCHEMBL8460073 0.78 L3MBTL1 (0.60) MGLLALDH1A1MAPTPOLBHSD17B10
SCHEMBL28348424 0.78 MGLL (0.53) MGLLALDH1A1MAPTPOLBHSD17B10
SCHEMBL2550818 0.78 MGLL (0.53) MGLLALDH1A1MAPTPOLBHSD17B10
SCHEMBL24034719 0.78 MGLL (0.62) MGLLALDH1A1MAPTPOLBHSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0010107-B1 REPELLENT AGAINST AQUATIC ORGANISMS IHARA CHEMICAL INDUSTRY Co., Ltd. (JP) 1983-04-13 EP disclosed
EP-0010107-A1 REPELLENT AGAINST AQUATIC ORGANISMS IHARA CHEMICAL INDUSTRY Co., Ltd. (JP) 1980-04-30 EP disclosed
US-4111879-A RESIN AND AN N-ARYL-MALEIMIDE IHARA CHEMICAL INDUSTRY CO., LTD. (JP) 1978-09-05 US disclosed