Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASP2 | P42575 | 1/20 | 0.61 |
| ▸ | NAAA | Q02083 | 1/20 | 0.57 |
| ▸ | DPP7 | Q9UHL4 | 2/20 | 0.54 |
| ▸ | RRM1 | P23921 | 1/20 | 0.54 |
| ▸ | NOD1 | Q9Y239 | 3/20 | 0.52 |
| ▸ | GNAI3 | P08754 | 1/20 | 0.51 |
| ▸ | GNAO1 | P09471 | 1/20 | 0.51 |
| ▸ | GNAI1 | P63096 | 1/20 | 0.51 |
| ▸ | FAAH | O00519 | 3/20 | 0.50 |
| ▸ | SLC6A5 | Q9Y345 | 2/20 | 0.49 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.47 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.47 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7349053 | 1.00 | CASP2 (0.61) | CASP2NAAADPP7RRM1NOD1 | |
| SCHEMBL14381165 | 0.93 | NOD1 (0.50) | CASP2NAAADPP7RRM1NOD1 | |
| SCHEMBL22646981 | 0.91 | NOD1 (0.59) | CASP2NAAADPP7RRM1NOD1 | |
| SCHEMBL6698108 | 0.87 | NOD1 (0.66) | CASP2NAAADPP7RRM1NOD1 | |
| SCHEMBL31251746 | 0.87 | DPP7 (0.73) | CASP2NAAADPP7RRM1NOD1 | |
| SCHEMBL24072850 | 0.87 | DPP7 (0.73) | CASP2NAAADPP7RRM1NOD1 | |
| SCHEMBL23895012 | 0.87 | DPP7 (0.73) | CASP2NAAADPP7RRM1NOD1 | |
| SCHEMBL31619646 | 0.87 | DPP7 (0.73) | CASP2NAAADPP7RRM1NOD1 | |
| SCHEMBL31619668 | 0.87 | DPP7 (0.73) | CASP2NAAADPP7RRM1NOD1 | |
| SCHEMBL27717842 | 0.87 | NOD1 (0.66) | CASP2NAAADPP7RRM1NOD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0021367-B1 | MURAMYLDIPEPTIDE DERIVATIVES, PROCESS FOR PREPARING SAID COMPOUNDS AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAID COMPOUNDS | DAIICHI SEIYAKU CO., LTD. (JP) | 1983-04-06 | — | — | EP | disclosed |