Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | LPAR5 | Q9H1C0 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25902381 | 0.84 | THRB (0.40) | THRBUSP2HSD17B10KDM4EHTT | |
| SCHEMBL15965450 | 0.84 | MEN1 (0.43) | THRBUSP2HSD17B10ALDH1A1KDM4E | |
| SCHEMBL7901287 | 0.84 | HSD17B10 (0.44) | USP2HSD17B10ALDH1A1KDM4EPOLB | |
| SCHEMBL31505845 | 0.84 | — | — | |
| SCHEMBL997153 | 0.84 | — | — | |
| SCHEMBL13243216 | 0.84 | — | — | |
| SCHEMBL9719570 | 0.83 | ALDH1A1 (0.48) | THRBUSP2HSD17B10ALDH1A1KDM4E | |
| SCHEMBL7206346 | 0.82 | MEN1 (0.52) | THRBUSP2HSD17B10ALDH1A1HTT | |
| SCHEMBL9736299 | 0.82 | HSD17B10 (0.56) | THRBUSP2HSD17B10ALDH1A1KDM4E | |
| SCHEMBL20262946 | 0.82 | MEN1 (0.52) | THRBUSP2HSD17B10ALDH1A1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0080529-A1 | 2-Cyano-substituted 1,3-dioxane and dioxolane derivatives | THE DOW CHEMICAL COMPANY (US) | 1983-06-08 | — | — | EP | disclosed |
| US-4365073-A | Derivatives of cyano-substituted ketones and aldehydes | THE DOW CHEMICAL COMPANY (US) | 1982-12-21 | — | — | US | disclosed |