Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11214093 | 0.91 | LMNA (0.38) | LMNADNM1 | |
| SCHEMBL11211511 | 0.85 | LMNA (0.41) | LMNAHSD17B10 | |
| SCHEMBL6376885 | 0.82 | LMNA (0.43) | LMNADNM1HSD17B10 | |
| SCHEMBL531227 | 0.82 | LMNA (0.53) | LMNAHSD17B10 | |
| SCHEMBL11209725 | 0.81 | LMNA (0.38) | LMNADNM1 | |
| SCHEMBL3278376 | 0.80 | — | — | |
| SCHEMBL28167608 | 0.80 | DNM1 (0.46) | LMNADNM1 | |
| SCHEMBL25505152 | 0.78 | DNM1 (0.50) | LMNADNM1 | |
| SCHEMBL11213307 | 0.78 | — | — | |
| SCHEMBL8899889 | 0.77 | LMNA (0.52) | LMNADNM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4398913-A | ALKALINE PASTES | CASSELLA AKTIENGESELLSCHAFT (DE) | 1983-08-16 | — | — | US | disclosed |