Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRC | P12931 | 2/20 | 0.69 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 3/20 | 0.39 |
| ▸ | CA1 | P00915 | 2/20 | 0.39 |
| ▸ | CA12 | O43570 | 1/20 | 0.39 |
| ▸ | CA9 | Q16790 | 1/20 | 0.39 |
| ▸ | ESR1 | P03372 | 3/20 | 0.38 |
| ▸ | ESR2 | Q92731 | 3/20 | 0.38 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.37 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.37 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.36 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.36 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.36 |
| ▸ | PTPN6 | P29350 | 2/20 | 0.36 |
| ▸ | PTPN11 | Q06124 | 2/20 | 0.36 |
| ▸ | HTR3A | P46098 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.36 |
| ▸ | PEPD | P12955 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11218064 | 0.82 | SRC (0.47) | SRCLMNACA2CA1CA12 | |
| SCHEMBL11212883 | 0.82 | SRC (0.47) | SRCLMNAHIF1ATSHRNFKB1 | |
| SCHEMBL11212252 | 0.82 | SRC (0.47) | SRCLMNACA2CA1ALDH1A1 | |
| SCHEMBL11216181 | 0.82 | PTPN1 (0.50) | SRCLMNACA2CA1CA12 | |
| SCHEMBL13619014 | 0.82 | SRC (0.70) | SRCCA2CA1CA12CA9 | |
| SCHEMBL7898010 | 0.82 | SRC (1.00) | SRCLMNACA2CA1CA12 | |
| SCHEMBL9706850 | 0.82 | SRC (0.70) | SRCCA2CA1CA12CA9 | |
| SCHEMBL11211513 | 0.80 | SRC (0.69) | SRCLMNACA2CA1CA12 | |
| SCHEMBL6381902 | 0.80 | SRC (0.96) | SRCLMNACA2CA1CA12 | |
| SCHEMBL11218212 | 0.78 | ALOX5 (0.49) | SRCCA2CA1CA9TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4329454-A | Cephalosporin compounds | ELI LILLY AND COMPANY (US) | 1982-05-11 | — | — | US | disclosed |