Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRR1 | P24046 | 2/20 | 0.37 |
| ▸ | GABRR2 | P28476 | 2/20 | 0.37 |
| ▸ | BLM | P54132 | 2/20 | 0.37 |
| ▸ | GABRR3 | A8MPY1 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | APEX1 | P27695 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11211566 | 1.00 | GABRR1 (0.37) | GABRR1GABRR2BLMGABRR3LMNA | |
| Hydrochloric Acid SCHEMBL11624764 | 0.98 | GABRR1 (0.35) | GABRR1GABRR2BLMGABRR3LMNA | |
| Hydrochloric Acid SCHEMBL11228346 | 0.98 | GABRR1 (0.35) | GABRR1GABRR2BLMGABRR3LMNA | |
| SCHEMBL11239601 | 0.85 | — | — | |
| SCHEMBL11227969 | 0.78 | — | — | |
| Hydrochloric Acid SCHEMBL11234488 | 0.77 | — | — | |
| SCHEMBL11238032 | 0.75 | — | — | |
| SCHEMBL11235005 | 0.75 | MTNR1A (0.32) | — | |
| Bromide SCHEMBL11241577 | 0.74 | MTNR1A (0.31) | — | |
| SCHEMBL11241097 | 0.74 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4399151-A | USING A-SUBSTITUTERD AMINES OR A-SUBSTITUTED AMINO ACIDS | MERRELL DOW PHARMACEUTICALS INC. (US) | 1983-08-16 | — | — | US | disclosed |
| US-4336054-A | AMINO ACIDS | MERRELL DOW PHARMACEUTICALS INC. (US) | 1982-06-22 | — | — | US | disclosed |