Known targets — ChEMBL curated mechanism
ACHEADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3APH1AAPH1BCHRM2CHRM3EZH2GRIN2AHTR1AHTR1BHTR1DHTR1FHTR3ANCSTNP2RY12PSEN1PSEN2PSENENSIGMAR1SLC6A2SLC6A3SLC6A4
The experimentally established mechanism targets of Bromide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11235005 | 0.98 | MTNR1A (0.32) | MTNR1AMTNR1B | |
| SCHEMBL11241097 | 0.81 | — | — | |
| SCHEMBL11227664 | 0.76 | MTNR1A (0.32) | MTNR1AMTNR1B | |
| SCHEMBL11211564 | 0.74 | GABRR1 (0.37) | — | |
| SCHEMBL11211566 | 0.74 | GABRR1 (0.37) | — | |
| Hydrochloric Acid SCHEMBL11624764 | 0.73 | GABRR1 (0.35) | — | |
| Hydrochloric Acid SCHEMBL11228346 | 0.73 | GABRR1 (0.35) | — | |
| SCHEMBL11239601 | 0.71 | — | — | |
| SCHEMBL11240400 | 0.67 | — | — | |
| SCHEMBL13397644 | 0.66 | KDM4E (0.46) | MTNR1AMTNR1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4323704-A | ENZYME INHIBITORS USEFUL AGAINST BACTERIA, FUNGUS AND VIRAL INFECTIONS, MALE ANTIFERTILITY AGENTS, IMMUNO-SUPPRESSANTS, AND ANTITUMOR ACTIVITY | MERRELL TORAUDE ET COMPAGNIE (FR) | 1982-04-06 | — | — | US | disclosed |
| US-4267374-A | BACTERICIDES; VIRICIDES; FUNGICIDES; INHIBITORS OF HYDROLASE ENZYMES; INTERMEDIATE FOR CEPHALOSPORIN COMPOUND | MERRELL TORAUDE ET COMPAGNIE (FR) | 1981-05-12 | — | — | US | disclosed |