Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.71 |
| ▸ | MEN1 | O00255 | 2/20 | 0.71 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.71 |
| ▸ | TP53 | P04637 | 4/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.62 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.62 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.58 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 3/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | FNIP1 | Q8TF40 | 1/20 | 0.36 |
| ▸ | FEM1B | Q9UK73 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11216023 | 0.93 | TP53 (0.74) | TDP1MEN1KMT2ATP53ALDH1A1 | |
| SCHEMBL11213590 | 0.86 | ALDH1A1 (0.60) | TDP1MEN1KMT2ATP53ALDH1A1 | |
| SCHEMBL9613872 | 0.85 | TDP1 (0.80) | TDP1MEN1KMT2ATP53ALDH1A1 | |
| SCHEMBL9614001 | 0.85 | TDP1 (0.85) | TDP1MEN1KMT2ATP53ALDH1A1 | |
| SCHEMBL9420240 | 0.84 | TP53 (0.84) | TDP1MEN1KMT2ATP53ALDH1A1 | |
| Butachlor SCHEMBL65784 | 0.83 | TDP1 (1.00) | TDP1MEN1KMT2ATP53ALDH1A1 | |
| Butachlor SCHEMBL4891145 | 0.83 | TDP1 (1.00) | TDP1MEN1KMT2ATP53ALDH1A1 | |
| SCHEMBL11873688 | 0.80 | TP53 (0.62) | TDP1MEN1KMT2ATP53ALDH1A1 | |
| SCHEMBL10495725 | 0.79 | TDP1 (0.70) | TDP1MEN1KMT2ATP53ALDH1A1 | |
| Butachlor SCHEMBL11052762 | 0.79 | TDP1 (0.90) | TDP1MEN1KMT2ATP53ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4319917-A | N-(2-Cyanoalkoxy)methyl-N-(2-,3-, or 6-alkylphenyl)-α-haloacetamides | PPG INDUSTRIES, INC. (US) | 1982-03-16 | — | — | US | claimed |
| US-4319917-A | N-(2-Cyanoalkoxy)methyl-N-(2-,3-, or 6-alkylphenyl)-α-haloacetamides | PPG INDUSTRIES, INC. (US) | 1982-03-16 | — | — | US | disclosed |