Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | CNR2 | P34972 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | TP53 | P04637 | 2/20 | 0.39 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.38 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.37 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10932148 | 0.89 | TSHR (0.53) | TSHRPOLBALDH1A1USP2HSD17B10 | |
| SCHEMBL11218305 | 0.88 | CYP2C19 (0.57) | TSHRPOLBCNR2ALDH1A1USP2 | |
| SCHEMBL11211191 | 0.84 | ALDH1A1 (0.52) | TSHRCNR2ALDH1A1CYP2C19GAA | |
| SCHEMBL6555348 | 0.81 | POLB (0.48) | TSHRPOLBCNR2ALDH1A1USP2 | |
| SCHEMBL150182 | 0.80 | TSHR (0.50) | TSHRPOLBCNR2ALDH1A1USP2 | |
| SCHEMBL2323987 | 0.79 | USP2 (0.53) | TSHRPOLBALDH1A1USP2HSD17B10 | |
| SCHEMBL11702190 | 0.78 | USP2 (0.46) | TSHRPOLBCNR2ALDH1A1USP2 | |
| Methane SCHEMBL27491555 | 0.78 | USP2 (0.50) | TSHRPOLBCNR2ALDH1A1USP2 | |
| SCHEMBL24405300 | 0.78 | POLB (0.46) | TSHRPOLBCNR2ALDH1A1USP2 | |
| SCHEMBL20119625 | 0.78 | TSHR (0.81) | TSHRCNR2ALDH1A1CYP2C19TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4313872-A | MONDAZO AND DISAZO DYES | CASSELLA AKTIENGESELLSCHAFT (DE) | 1982-02-02 | — | — | US | disclosed |