Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 2/20 | 0.42 |
| ▸ | NFE2L2 | Q16236 | 3/20 | 0.41 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.41 |
| ▸ | MAOA | P21397 | 1/20 | 0.41 |
| ▸ | APP | P05067 | 3/20 | 0.36 |
| ▸ | RELA | Q04206 | 3/20 | 0.36 |
| ▸ | TRPA1 | O75762 | 2/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11212004 | 1.00 | MAOB (0.42) | MAOBNFE2L2CYP19A1MAOAAPP | |
| SCHEMBL11209918 | 1.00 | MAOB (0.42) | MAOBNFE2L2CYP19A1MAOAAPP | |
| SCHEMBL8447454 | 0.87 | NFE2L2 (0.56) | NFE2L2RELACA1ALDH1A1ALOX5 | |
| SCHEMBL888505 | 0.87 | NFE2L2 (0.56) | NFE2L2RELACA1ALDH1A1ALOX5 | |
| SCHEMBL6886036 | 0.87 | ALDH1A1 (0.48) | ALDH1A1LMNAMAPK1 | |
| SCHEMBL24768620 | 0.87 | NFE2L2 (0.56) | NFE2L2RELACA1ALDH1A1ALOX5 | |
| SCHEMBL331174 | 0.86 | — | — | |
| SCHEMBL13704159 | 0.86 | — | — | |
| SCHEMBL1641281 | 0.86 | — | — | |
| SCHEMBL2173470 | 0.85 | NFE2L2 (0.64) | NFE2L2APPTRPA1ALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4417039-A | Cis-enyne aromatic and aromatic heterocyclic polymers | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE AIR FORCE (US) | 1983-11-22 | — | — | US | disclosed |
| US-4417039-A | Cis-enyne aromatic and aromatic heterocyclic polymers | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE AIR FORCE (US) | 1983-11-22 | — | — | US | disclosed |