Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 5/20 | 0.70 |
| ▸ | PNMT | P11086 | 1/20 | 0.66 |
| ▸ | MAOA | P21397 | 1/20 | 0.58 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.56 |
| ▸ | RXRA | P19793 | 1/20 | 0.56 |
| ▸ | RXRB | P28702 | 1/20 | 0.56 |
| ▸ | RXRG | P48443 | 1/20 | 0.56 |
| ▸ | DHFR | P00374 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9626343 | 0.87 | MAOB (0.67) | MAOBPNMTMAOAALOX5RXRA | |
| SCHEMBL9626469 | 0.85 | MAOB (0.66) | MAOBPNMTMAOAALOX5RXRA | |
| Isopropylamine SCHEMBL9628060 | 0.85 | MAOB (0.65) | MAOBPNMTMAOARXRARXRB | |
| SCHEMBL9627307 | 0.85 | MAOB (0.71) | MAOBMAOAALOX5RXRARXRB | |
| SCHEMBL9628042 | 0.85 | MAOB (0.61) | MAOBMAOAALOX5RXRARXRB | |
| SCHEMBL9626485 | 0.84 | SLC6A2 (0.70) | MAOBMAOA | |
| SCHEMBL21234325 | 0.83 | MAOB (0.67) | MAOBMAOAALOX5RXRARXRB | |
| SCHEMBL12532788 | 0.83 | LTA4H (0.67) | MAOBMAOA | |
| SCHEMBL2750285 | 0.83 | LTA4H (0.67) | MAOBMAOA | |
| SCHEMBL2750286 | 0.83 | LTA4H (0.67) | MAOBMAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4329367-A | ANTIHYPERTENSIVE AGENTS | CIBA-GEIGY CORPORATION (US) | 1982-05-11 | — | — | US | disclosed |