Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 6/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.38 |
| ▸ | GMNN | O75496 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | THPO | P40225 | 1/20 | 0.38 |
| ▸ | MTOR | P42345 | 1/20 | 0.38 |
| ▸ | BLM | P54132 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23219748 | 1.00 | LMNA (0.48) | LMNAALDH1A1HSD17B10MEN1KMT2A | |
| SCHEMBL117119 | 0.92 | LMNA (0.44) | LMNAALDH1A1HSD17B10MEN1KMT2A | |
| SCHEMBL1618085 | 0.92 | LMNA (0.44) | LMNAALDH1A1HSD17B10MEN1KMT2A | |
| SCHEMBL9949550 | 0.91 | ALDH1A1 (0.43) | LMNAALDH1A1HSD17B10MEN1KMT2A | |
| SCHEMBL1619918 | 0.90 | LMNA (0.45) | LMNAALDH1A1HSD17B10MEN1KMT2A | |
| SCHEMBL26999627 | 0.89 | LMNA (0.46) | LMNAALDH1A1HSD17B10MEN1KMT2A | |
| SCHEMBL31284732 | 0.89 | LMNA (0.46) | LMNAALDH1A1HSD17B10MEN1KMT2A | |
| SCHEMBL30786802 | 0.89 | LMNA (0.46) | LMNAALDH1A1HSD17B10MEN1KMT2A | |
| Hydrochloric Acid SCHEMBL9803172 | 0.88 | LMNA (0.45) | LMNAALDH1A1HSD17B10MEN1KMT2A | |
| Hydrochloric Acid SCHEMBL7879376 | 0.88 | LMNA (0.45) | LMNAALDH1A1HSD17B10MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0013072-B1 | LONG CHAIN AMINE DERIVATIVES AND PROCESS FOR THEIR PREPARATION | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1983-04-13 | — | — | EP | disclosed |