SCHEMBL112123

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL111889	0.84	CXCR3 (0.67)	CXCR3KCNH2HSD17B10SMN1; SMN2KMT2A
	SCHEMBL112547	0.83	CXCR3 (0.54)	CXCR3KCNH2KDM4ERAB9AMEN1
	SCHEMBL113241	0.82	CXCR3 (0.53)	CXCR3KCNH2KDM4EHSD17B10HPGD
	SCHEMBL111164	0.82	CXCR3 (0.59)	CXCR3KCNH2HSD17B10HPGDSMN1; SMN2
	SCHEMBL110498	0.82	CXCR3 (0.59)	CXCR3KCNH2HSD17B10HPGDSMN1; SMN2
	SCHEMBL111833	0.82	CXCR3 (0.61)	CXCR3KCNH2HSD17B10SMN1; SMN2KMT2A
	SCHEMBL112597	0.81	CXCR3 (0.58)	CXCR3KCNH2HSD17B10SMN1; SMN2KMT2A
	SCHEMBL114642	0.81	CXCR3 (0.58)	CXCR3KCNH2KDM4EHSD17B10HPGD
	SCHEMBL112499	0.81	CXCR3 (0.54)	CXCR3KCNH2KMT2AIRAK4ALDH1A1
	SCHEMBL112255	0.81	CXCR3 (0.55)	CXCR3KCNH2KDM4EHSD17B10RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.