SCHEMBL11212707

CC[C@H](C)[C@H](NC(=O)[C@@H](N)Cc1ccc(O)cc1)C(=O)N[C@@H](Cc1c[nH]cn1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](C)C(=O)O

nearest known ligand 0.54

Predicted protein targets (top 8)

	gene	UniProt	supporting neighbours	confidence
▸	AGTR1	P30556	3/20	0.54

▸	SLC6A2	P23975	1/20	0.53

▸	AGTR2	P50052	1/20	0.52

▸	NTSR2	O95665	10/20	0.51

▸	NTSR1	P30989	10/20	0.51

▸	SORT1	Q99523	9/20	0.51

▸	LNPEP	Q9UIQ6	4/20	0.50

▸	ANPEP	P15144	2/20	0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL11212701	1.00	AGTR1 (0.54)	AGTR1SLC6A2AGTR2NTSR2NTSR1
SCHEMBL29701255	0.93	SLC6A2 (0.63)	AGTR1SLC6A2AGTR2NTSR2NTSR1
SCHEMBL29966464	0.92	LNPEP (0.49)	AGTR1SLC6A2AGTR2NTSR2NTSR1
SCHEMBL11204440	0.92	LNPEP (0.60)	AGTR1AGTR2NTSR2NTSR1SORT1
SCHEMBL11204436	0.92	LNPEP (0.60)	AGTR1AGTR2NTSR2NTSR1SORT1
SCHEMBL10066200	0.87	AGTR1 (0.62)	AGTR1SLC6A2AGTR2NTSR2NTSR1
SCHEMBL29975776	0.87	AGTR1 (0.57)	AGTR1AGTR2NTSR2NTSR1SORT1
SCHEMBL11208028	0.87	AGTR1 (0.46)	AGTR1SLC6A2AGTR2NTSR2NTSR1
SCHEMBL29448041	0.86	SLC6A2 (0.65)	AGTR1SLC6A2AGTR2LNPEPANPEP
SCHEMBL30670298	0.86	AGTR1 (0.62)	AGTR1SLC6A2AGTR2NTSR2NTSR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
EP-0034260-B1	PEPTIDES, PROCESS FOR THEIR PREPARATION AND MEDICAMENTS OR DIAGNOSTIC AGENTS CONTAINING THEM	RICHTER GEDEON VEGYESZETI GYAR R.T. (HU)	1983-07-20	—	—	EP	disclosed