SCHEMBL11212892

SCHEMBL11212892

C=CCc1ncccc1-c1ccccc1

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ADRB2 P07550 1/20 0.39
ADRB1 P08588 1/20 0.39
L3MBTL1 Q9Y468 2/20 0.37
TOP1 P11387 1/20 0.37
HTT P42858 4/20 0.36
ALDH1A1 P00352 2/20 0.36
HSD17B10 Q99714 1/20 0.36
PTGS1 P23219 1/20 0.36
PTGS2 P35354 1/20 0.36
AGTR1 P30556 1/20 0.35
AGTR2 P50052 1/20 0.35
GABRA1 P14867 1/20 0.34
GABRB2 P47870 1/20 0.34
KDM4E B2RXH2 2/20 0.34
KCNA5 P22460 1/20 0.34
KCNH2 Q12809 1/20 0.34
LMNA P02545 2/20 0.34
BACE1 P56817 1/20 0.33
CHRNB2 P17787 1/20 0.33
CHRNB4 P30926 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28085918 0.85 MMP9 (0.36) L3MBTL1HTTALDH1A1HSD17B10AGTR1
SCHEMBL9729051 0.79 DPP4 (0.35) L3MBTL1TOP1HTTALDH1A1HSD17B10
SCHEMBL676668 0.79 ALDH1A1 (0.57) L3MBTL1TOP1HTTALDH1A1HSD17B10
SCHEMBL30022235 0.77 ALDH1A1 (0.41) L3MBTL1TOP1HTTALDH1A1HSD17B10
SCHEMBL25452791 0.76 PTGS1 (0.35) L3MBTL1TOP1HTTALDH1A1HSD17B10
SCHEMBL11311948 0.76 TOP1 (0.40) L3MBTL1TOP1HTTALDH1A1HSD17B10
SCHEMBL2181299 0.76 DPP4 (0.50) ADRB2L3MBTL1TOP1HTTALDH1A1
SCHEMBL8150056 0.76 PTGS1 (0.42) ADRB2L3MBTL1TOP1HTTALDH1A1
SCHEMBL9491684 0.74 KDM4E (0.43) L3MBTL1TOP1HTTALDH1A1HSD17B10
SCHEMBL11552073 0.74 KDM4E (0.43) L3MBTL1TOP1HTTALDH1A1HSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109970804-B Organic metal iridium complex and application thereof 江苏三月科技股份有限公司 2022-02-22 CN disclosed
CN-109970809-B Metal iridium complex and application thereof 中节能万润股份有限公司 2021-07-27 CN disclosed
EP-0069521-A2 Pyridinyl and imidazolyl derivatives of benzofurans and benzothiophenes THE UPJOHN COMPANY (US) 1983-01-12 EP disclosed