Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARB | P10826 | 7/20 | 0.58 |
| ▸ | RARG | P13631 | 7/20 | 0.58 |
| ▸ | RARA | P10276 | 6/20 | 0.58 |
| ▸ | PTGS1 | P23219 | 7/20 | 0.56 |
| ▸ | PTGS2 | P35354 | 7/20 | 0.56 |
| ▸ | RXRA | P19793 | 2/20 | 0.53 |
| ▸ | NOTUM | Q6P988 | 2/20 | 0.44 |
| ▸ | ALOX5 | P09917 | 4/20 | 0.41 |
| ▸ | CYP26A1 | O43174 | 1/20 | 0.40 |
| ▸ | CYP26B1 | Q9NR63 | 1/20 | 0.40 |
| ▸ | CNR2 | P34972 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1018488 | 0.87 | RARB (0.45) | RARBRARGRARAPTGS1PTGS2 | |
| SCHEMBL3547915 | 0.85 | RARB (0.63) | RARBRARGRARAPTGS1PTGS2 | |
| SCHEMBL3542625 | 0.85 | RARB (0.71) | RARBRARGRARAPTGS1PTGS2 | |
| SCHEMBL9133271 | 0.84 | RARB (0.60) | RARBRARGRARAPTGS1PTGS2 | |
| Hydrochloric Acid SCHEMBL11212968 | 0.84 | RARB (0.69) | RARBRARGRARAPTGS1PTGS2 | |
| SCHEMBL13668358 | 0.83 | RARB (0.41) | RARBRARGRARAPTGS1PTGS2 | |
| SCHEMBL5658641 | 0.81 | PTGS2 (0.64) | RARBRARGRARAPTGS1PTGS2 | |
| SCHEMBL16744298 | 0.81 | RARB (0.73) | RARBRARGRARAPTGS1PTGS2 | |
| SCHEMBL5656242 | 0.81 | RARB (0.55) | RARBRARGRARAPTGS1PTGS2 | |
| SCHEMBL5654554 | 0.81 | RARB (0.55) | RARBRARGRARAPTGS1PTGS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4333759-A | Herbicidal 5-cyano-2,3-dihydro-benzofuran-2-ones | FISONS LIMITED (GB) | 1982-06-08 | — | — | US | disclosed |
| US-4263037-A | 5-Cyano-2,3-dihydrobenzofurans useful as herbicides | FISONS LIMITED (GB) | 1981-04-21 | — | — | US | disclosed |
| EP-0007719-A2 | Cyanbenzofuran derivatives, processes for their preparation and their use in herbicidal compositions; cyanobenzene, benzodioxepine, benzodioxaphosphepine and benzodioxathiepine derivatives | FBC LIMITED (GB) | 1980-02-06 | — | — | EP | disclosed |