Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARB | P10826 | 8/20 | 0.60 |
| ▸ | RARG | P13631 | 8/20 | 0.60 |
| ▸ | RARA | P10276 | 6/20 | 0.60 |
| ▸ | RXRA | P19793 | 4/20 | 0.55 |
| ▸ | CYP26A1 | O43174 | 1/20 | 0.55 |
| ▸ | CYP26B1 | Q9NR63 | 1/20 | 0.55 |
| ▸ | HNF4A | P41235 | 2/20 | 0.46 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.42 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.42 |
| ▸ | SSTR5 | P35346 | 2/20 | 0.42 |
| ▸ | RXRB | P28702 | 1/20 | 0.40 |
| ▸ | RXRG | P48443 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2240304 | 0.86 | RARB (0.76) | RARBRARGRARARXRACYP26A1 | |
| SCHEMBL2240683 | 0.86 | RARB (0.64) | RARBRARGRARARXRACYP26A1 | |
| Hydrochloric Acid SCHEMBL9133279 | 0.85 | RARB (0.74) | RARBRARGRARARXRACYP26A1 | |
| SCHEMBL11212966 | 0.84 | RARB (0.58) | RARBRARGRARARXRACYP26A1 | |
| SCHEMBL12465802 | 0.81 | RARA (0.56) | RARBRARGRARARXRACYP26A1 | |
| SCHEMBL10563217 | 0.81 | RARB (0.70) | RARBRARGRARARXRACYP26A1 | |
| SCHEMBL10566002 | 0.80 | RARB (0.55) | RARBRARGRARARXRACYP26A1 | |
| SCHEMBL10933609 | 0.80 | RARB (0.57) | RARBRARGRARARXRACYP26A1 | |
| SCHEMBL9095816 | 0.79 | RARG (0.75) | RARBRARGRARARXRACYP26A1 | |
| Terephthalic Acid SCHEMBL27345449 | 0.78 | RARB (0.66) | RARBRARGRARARXRACYP26A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5428052-A | Classifiable as retinoids; skin disorders, corneopathy | CENTRE INTERNATIONALE DE RECHERCHES DERMATOLOGIQUES (C.I.R.D.) (FR) | 1995-06-27 | — | — | US | disclosed |
| US-5288744-A | Tetramethyltetrahydronaphthyl benzothiazole for treating skin disorders | CENTRE INTERNATIONAL DE RECHERCHES DERMATOLOGIQUES (C.I.R.D.) (FR) | 1994-02-22 | — | — | US | disclosed |
| US-5260295-A | Retinoic acid derivatives, cosmetics, skin disorders | CENTRE INTERNATIONAL DE RECHERCHES DERMATOLOGIQUES (C.I.R.D.) (FR) | 1993-11-09 | — | — | US | disclosed |
| US-5059621-A | Treatment of dermatologic ailments linked to keratinization disorder | CENTRE INTERNATIONAL DE RECHERCHES DERMATOLOGIQUES (C.I.R.D.) (FR) | 1991-10-22 | — | — | US | disclosed |
| US-4920140-A | Skin disorders | CENTRE INTERNATIONAL DE RECHERCHES DERMATOLOGIQUES C.I.R.D. (FR) | 1990-04-24 | — | — | US | disclosed |
| US-4740519-A | Benzo (b) thiophene carboxylate derivatives and pharmaceutical compositions | CENTRE INTERNATIONAL DE RECHERCHES DERMATOLOGIQUES C.I.R.D. (FR) | 1988-04-26 | — | — | US | disclosed |