Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | CHRNB4 | P30926 | 2/20 | 0.37 |
| ▸ | CHRNA3 | P32297 | 2/20 | 0.37 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.37 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.37 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.35 |
| ▸ | LTA4H | P09960 | 3/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11211604 | 0.81 | SMN1; SMN2 (0.47) | SMN1; SMN2MEN1KMT2ALMNAALDH1A1 | |
| SCHEMBL11007300 | 0.79 | SMN1; SMN2 (0.50) | SMN1; SMN2MEN1KMT2ALMNAALDH1A1 | |
| SCHEMBL11213123 | 0.78 | ALDH1A1 (0.45) | SMN1; SMN2MEN1KMT2ALMNAALDH1A1 | |
| SCHEMBL11149870 | 0.78 | ALDH1A1 (0.36) | MEN1KMT2AALDH1A1MAPTHPGD | |
| SCHEMBL11217173 | 0.76 | SMN1; SMN2 (0.43) | SMN1; SMN2MEN1KMT2ALMNAALDH1A1 | |
| SCHEMBL11214418 | 0.75 | SMN1; SMN2 (0.50) | SMN1; SMN2MEN1KMT2ALMNAALDH1A1 | |
| SCHEMBL11348058 | 0.75 | CHRM2 (0.48) | SMN1; SMN2MEN1KMT2ALMNAALDH1A1 | |
| SCHEMBL15222055 | 0.73 | SMN1; SMN2 (0.54) | SMN1; SMN2MEN1KMT2ALMNAALDH1A1 | |
| SCHEMBL680143 | 0.73 | SMN1; SMN2 (0.54) | SMN1; SMN2MEN1KMT2ALMNAALDH1A1 | |
| SCHEMBL11219193 | 0.72 | SMN1; SMN2 (0.45) | SMN1; SMN2MEN1KMT2ALMNAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4332937-A | DYES FOR POLYACRYLONITRILE | CIBA-GEIGY CORPORATION (US) | 1982-06-01 | — | — | US | disclosed |