Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.54 |
| ▸ | MEN1 | O00255 | 3/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | CHRNB4 | P30926 | 2/20 | 0.41 |
| ▸ | CHRNA3 | P32297 | 2/20 | 0.41 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.41 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.38 |
| ▸ | LTA4H | P09960 | 1/20 | 0.38 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15222055 | 1.00 | SMN1; SMN2 (0.54) | SMN1; SMN2MEN1KMT2AALDH1A1LMNA | |
| SCHEMBL15222072 | 0.81 | ITGB2 (0.45) | SMN1; SMN2MEN1KMT2AALDH1A1LMNA | |
| SCHEMBL19418197 | 0.79 | SMN1; SMN2 (0.45) | SMN1; SMN2MEN1KMT2AALDH1A1LMNA | |
| SCHEMBL15500970 | 0.79 | CHRNB4 (0.44) | SMN1; SMN2MEN1KMT2ALMNAMAPT | |
| SCHEMBL11214236 | 0.77 | LMNA (0.54) | SMN1; SMN2ALDH1A1LMNAMAPTCHRNB4 | |
| SCHEMBL13490300 | 0.77 | L3MBTL1 (0.41) | SMN1; SMN2ALDH1A1CHRNB4CHRNA3CHRNB2 | |
| SCHEMBL11007300 | 0.77 | SMN1; SMN2 (0.50) | SMN1; SMN2MEN1KMT2AALDH1A1LMNA | |
| SCHEMBL10222509 | 0.77 | SMN1; SMN2 (0.50) | SMN1; SMN2MEN1KMT2AALDH1A1LMNA | |
| SCHEMBL11210979 | 0.77 | HCRTR2 (0.41) | SMN1; SMN2MEN1KMT2AALDH1A1MAPT | |
| SCHEMBL11211604 | 0.76 | SMN1; SMN2 (0.47) | SMN1; SMN2MEN1KMT2AALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 222 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20190174759-A1 | FUNGICIDAL ACTIVE COMPOUND COMBINATIONS | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2019-06-13 | — | — | US | disclosed |
| US-10244755-B2 | Fungicidal active compound combinations | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2019-04-02 | — | — | US | disclosed |
| EP-2099751-B1 | BIPHENYL-SUBSTITUTED SPIROCYCLIC KETOENOLS | BAYER IP GMBH (DE) | 2018-05-30 | — | — | EP | disclosed |
| US-9968091-B2 | Selective herbicides based on substituted thien-3-yl-sulphonylamino(thio)carbonyltriazolin(thi)ones and safeners | BAYER CROPSCIENCE AG (DE) | 2018-05-15 | — | — | US | disclosed |
| US-9968091-B2 | Selective herbicides based on substituted thien-3-yl-sulphonylamino(thio)carbonyltriazolin(thi)ones and safeners | BAYER CROPSCIENCE AG (DE) | 2018-05-15 | — | — | US | disclosed |
| US-20160073635-A1 | SELECTIVE HERBICIDES BASED ON SUBSTITUTED THIEN-3-YL-SULPHONYLAMINO(THIO)CARBONYLTRIAZOLIN(THI)ONES AND SAFENERS | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2016-03-17 | — | — | US | disclosed |
| US-20160073635-A1 | SELECTIVE HERBICIDES BASED ON SUBSTITUTED THIEN-3-YL-SULPHONYLAMINO(THIO)CARBONYLTRIAZOLIN(THI)ONES AND SAFENERS | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2016-03-17 | — | — | US | disclosed |
| US-9259003-B2 | Insecticides based on neonicotinoids and safeners | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2016-02-16 | — | — | US | disclosed |
| US-9259003-B2 | Insecticides based on neonicotinoids and safeners | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2016-02-16 | — | — | US | disclosed |
| US-20160000076-A1 | Fungicidal Active Compound Combinations | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2016-01-07 | — | — | US | disclosed |
| US-20070015664-A1 | 2,4,6-Phenyl substituted cyclic ketoenols | BAYER CROPSCIENCE AG (DE) | 2007-01-18 | — | — | US | disclosed |
| EP-1429613-B1 | SELECTIVE HERBICIDES BASED ON SUBSTITUTED THIEN-3-YL-SULFONYLAMINO(THIO)CARBONYL-TRIAZOLIN(THI)ONES AND SAFENERS | BAYER CROPSCIENCE AG (DE) | 2007-01-17 | — | — | EP | disclosed |
| EP-0084853-B1 | PROCESS FOR THE PREPARATION OF 1,8-NAPHTHOLACTAM COMPOUNDS | CIBA-GEIGY AG (CH) | 1986-11-12 | — | — | EP | disclosed |
| US-4515963-A | AMIDATIUON OF NAPHTHOLACTONE | CIBA GEIGY AG (CH) | 1985-05-07 | — | — | US | disclosed |
| EP-0084853-A1 | Process for the preparation of 1,8-naphtholactam compounds | CIBA-GEIGY AG (CH) | 1983-08-03 | — | — | EP | disclosed |
| EP-0015872-B1 | CATIONIC AZODYESTUFFS, THEIR PREPARATION AND THEIR USE IN DYEING AND PRINTING TEXTILE MATERIAL | CIBA-GEIGY AG (CH) | 1983-03-30 | — | — | EP | disclosed |
| EP-0017621-B1 | DERIVATIVES OF NAPHTHOLACTAM, PROCESS FOR THEIR PREPARATION AND THEIR USE AS DYESTUFFS | CIBA-GEIGY AG (CH) | 1982-12-15 | — | — | EP | disclosed |
| US-4332937-A | DYES FOR POLYACRYLONITRILE | CIBA-GEIGY CORPORATION (US) | 1982-06-01 | — | — | US | disclosed |
| EP-0017621-A1 | Derivatives of naphtholactam, process for their preparation and their use as dyestuffs | CIBA-GEIGY AG (CH) | 1980-10-15 | — | — | EP | disclosed |
| EP-0015872-A1 | Cationic azodyestuffs, their preparation and their use in dyeing and printing textile material | CIBA-GEIGY AG (CH) | 1980-09-17 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190174759-A1 | FUNGICIDAL ACTIVE COMPOUND COMBINATIONS | DDT, CYP4X1, CYP51A1 | SMN1; SMN2 1812/4885MEN1 3706/4885KMT2A 1264/4885 |
| US-20070015664-A1 | 2,4,6-Phenyl substituted cyclic ketoenols | CYP4X1, KDM4E, KCNE1 | SMN1; SMN2 4514/4885MEN1 4847/4885KMT2A 321/4885 |
| US-10244755-B2 | Fungicidal active compound combinations | DDT, CYP4X1, CYP51A1 | SMN1; SMN2 1812/4885MEN1 3706/4885KMT2A 1264/4885 |
| US-20160073635-A1 | SELECTIVE HERBICIDES BASED ON SUBSTITUTED THIEN-3-YL-SULPHONYLAMINO(THIO)CARBONYLTRIAZOLIN(THI)ONES AND SAFENERS | TARS2, TST, TARS1 | SMN1; SMN2 2254/4885MEN1 4312/4885KMT2A 681/4885 |
| US-20160000076-A1 | Fungicidal Active Compound Combinations | DDT, CYP4X1, CYP51A1 | SMN1; SMN2 1812/4885MEN1 3706/4885KMT2A 1264/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.