SCHEMBL11213535

SCHEMBL11213535

CCCCCCCCCCCCCCCCCCOP(OCCO)OCC(C)(C)C

nearest known ligand 0.44

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 2/20 0.44
KMT2A Q03164 2/20 0.44
THRB P10828 1/20 0.44
HTT P42858 1/20 0.44
MAPT P10636 1/20 0.44
LMNA P02545 2/20 0.35
TSHR P16473 2/20 0.35
ALDH1A1 P00352 1/20 0.35
HSD17B10 Q99714 1/20 0.35
CES1 P23141 1/20 0.35
USP2 O75604 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.32
CES2 O00748 1/20 0.32
LPAR3 Q9UBY5 6/20 0.32
LPAR2 Q9HBW0 5/20 0.32
LPAR1 Q92633 2/20 0.32
NAAA Q02083 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11211884 1.00 MEN1 (0.44) MEN1KMT2ATHRBHTTMAPT
SCHEMBL10708378 0.79 MEN1 (0.38) MEN1KMT2ATHRBHTTMAPT
SCHEMBL6740549 0.77 THRB (0.47) MEN1KMT2ATHRBHTTMAPT
SCHEMBL11677867 0.77 THRB (0.47) MEN1KMT2ATHRBHTTMAPT
SCHEMBL98256 0.77 THRB (0.47) MEN1KMT2ATHRBHTTMAPT
SCHEMBL476658 0.77 THRB (0.47) MEN1KMT2ATHRBHTTMAPT
SCHEMBL39213 0.77 THRB (0.47) MEN1KMT2ATHRBHTTMAPT
SCHEMBL10390885 0.77 THRB (0.47) MEN1KMT2ATHRBHTTMAPT
SCHEMBL39064 0.77 THRB (0.47) MEN1KMT2ATHRBHTTMAPT
SCHEMBL100286 0.77 THRB (0.47) MEN1KMT2ATHRBHTTMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0019349-B1 STABILIZING COMPOSITION FOR POLYARYLENE ESTERS, STABILIZED POLYARYLENE ESTER, MOULDED ARTICLE PRODUCED THEREFROM AND PROCESS FOR STABILIZING A POLYARYLENE ESTER MONSANTO COMPANY (US) 1983-08-03 EP disclosed
EP-0019349-A1 Stabilizing composition for polyarylene esters, stabilized polyarylene ester, moulded article produced therefrom and process for stabilizing a polyarylene ester MONSANTO COMPANY (US) 1980-11-26 EP disclosed
US-4222932-A MOLDING MATERIALS STABILIZED BY ADDING AN AROMATIC ISOCYANATE AND AN ALIPHATIC PHOSPHITE MONSANTO COMPANY (US) 1980-09-16 US disclosed