Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 3/20 | 0.54 |
| ▸ | TP53 | P04637 | 1/20 | 0.53 |
| ▸ | HTT | P42858 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | MAPT | P10636 | 3/20 | 0.48 |
| ▸ | LMNA | P02545 | 3/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | DCPS | Q96C86 | 1/20 | 0.45 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.44 |
| ▸ | RXRA | P19793 | 1/20 | 0.42 |
| ▸ | RXRB | P28702 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | FABP4 | P15090 | 2/20 | 0.41 |
| ▸ | FABP5 | Q01469 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | FNTA | P49354 | 1/20 | 0.41 |
| ▸ | FNTB | P49356 | 1/20 | 0.41 |
| ▸ | CDK4 | P11802 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28497259 | 0.83 | HTT (0.56) | HPGDTP53HTTALDH1A1MAPT | |
| SCHEMBL11208852 | 0.83 | HPGD (0.43) | HPGDTP53HTTALDH1A1MAPT | |
| SCHEMBL16368767 | 0.80 | HPGD (0.40) | HPGDTP53HTTALDH1A1MAPT | |
| SCHEMBL11055202 | 0.80 | ALDH1A1 (0.59) | HPGDHTTALDH1A1MAPTLMNA | |
| SCHEMBL24831692 | 0.79 | MRGPRX4 (0.44) | HPGDHDAC8 | |
| SCHEMBL30786463 | 0.79 | MRGPRX4 (0.44) | HPGDHDAC8 | |
| SCHEMBL9068724 | 0.78 | ALDH1A1 (0.42) | HPGDTP53HTTALDH1A1MAPT | |
| SCHEMBL23679905 | 0.76 | HPGD (0.69) | HPGDHTTALDH1A1MAPTLMNA | |
| SCHEMBL16368766 | 0.76 | HPGD (0.69) | HPGDHTTALDH1A1MAPTLMNA | |
| SCHEMBL11215052 | 0.75 | SMN1; SMN2 (0.46) | ALDH1A1LMNAKDM4EPTPN1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0003257-B1 | COMBUSTION RESISTANT AROMATIC POLYMERS CONTAINING CHAR-FORMING BENZYL AND/OR ALLYL MOIETIES AND A COMBUSTION RETARDING AGENT | THE DOW CHEMICAL COMPANY (US) | 1983-10-05 | — | — | EP | disclosed |
| US-4360609-A | VINYLAROMATIC POLYMER, ACTIVE ALLYL OR BENZYL CARBON, ARYLSULFONATE CATALYST | THE DOW CHEMICAL COMPANY (US) | 1982-11-23 | — | — | US | disclosed |
| US-4224217-A | Combustion resistant aromatic polymers containing char-forming benzyl and/or allyl moieties | THE DOW CHEMICAL COMPANY (US) | 1980-09-23 | — | — | US | disclosed |
| EP-0003257-A1 | Combustion resistant aromatic polymers containing char-forming benzyl and/or allyl moieties and a combustion retarding agent | THE DOW CHEMICAL COMPANY (US) | 1979-08-08 | — | — | EP | disclosed |