Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | PTPRC | P08575 | 1/20 | 0.42 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.42 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.41 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.41 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.41 |
| ▸ | HTR1A | P08908 | 1/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.41 |
| ▸ | APP | P05067 | 1/20 | 0.40 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.40 |
| ▸ | F2 | P00734 | 1/20 | 0.40 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.40 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.40 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.40 |
| ▸ | TMPRSS6 | Q8IU80 | 1/20 | 0.40 |
| ▸ | ST14 | Q9Y5Y6 | 1/20 | 0.40 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8163506 | 0.89 | F2 (0.41) | SMN1; SMN2KDM4EPTPRCPTPN1F2 | |
| SCHEMBL8625765 | 0.83 | ALDH1A1 (0.51) | SMN1; SMN2KDM4EPTPRCPTPN1NPC1 | |
| SCHEMBL8166262 | 0.83 | MAOB (0.42) | SMN1; SMN2NPC1RAB9AALDH1A1MAOB | |
| SCHEMBL20855968 | 0.83 | CYSLTR1 (0.44) | PTPRCPTPN1SLC6A2SLC6A3F2 | |
| SCHEMBL8165404 | 0.82 | F2 (0.36) | SMN1; SMN2KDM4EPTPRCPTPN1APP | |
| SCHEMBL1200712 | 0.81 | SMN1; SMN2 (0.50) | SMN1; SMN2KDM4EPTPRCPTPN1SLC6A2 | |
| SCHEMBL8625003 | 0.80 | NPC1 (0.64) | KDM4ENPC1RAB9AALDH1A1MAOB | |
| SCHEMBL252296 | 0.79 | ALDH1A1 (0.43) | SMN1; SMN2ALDH1A1LMNA | |
| SCHEMBL2519657 | 0.79 | RAB9A (0.39) | SMN1; SMN2KDM4EPTPRCPTPN1KCNH2 | |
| SCHEMBL931875 | 0.79 | PTPRC (0.59) | SMN1; SMN2KDM4EPTPRCPTPN1SLC6A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0003257-B1 | COMBUSTION RESISTANT AROMATIC POLYMERS CONTAINING CHAR-FORMING BENZYL AND/OR ALLYL MOIETIES AND A COMBUSTION RETARDING AGENT | THE DOW CHEMICAL COMPANY (US) | 1983-10-05 | — | — | EP | disclosed |
| US-4360609-A | VINYLAROMATIC POLYMER, ACTIVE ALLYL OR BENZYL CARBON, ARYLSULFONATE CATALYST | THE DOW CHEMICAL COMPANY (US) | 1982-11-23 | — | — | US | disclosed |
| US-4224217-A | Combustion resistant aromatic polymers containing char-forming benzyl and/or allyl moieties | THE DOW CHEMICAL COMPANY (US) | 1980-09-23 | — | — | US | disclosed |
| EP-0003257-A1 | Combustion resistant aromatic polymers containing char-forming benzyl and/or allyl moieties and a combustion retarding agent | THE DOW CHEMICAL COMPANY (US) | 1979-08-08 | — | — | EP | disclosed |