SCHEMBL11213575

SCHEMBL11213575

Cc1nc(N)sc1C.Nc1ncc([N+](=O)[O-])s1

nearest known ligand 0.70

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.70
HPGD P15428 1/20 0.70
ALOX15 P16050 1/20 0.70
NOS1 P29475 2/20 0.52
MAPK8 P45983 1/20 0.43
MAPK9 P45984 1/20 0.43
MAPK10 P53779 1/20 0.43
NPC1 O15118 4/20 0.43
RAB9A P51151 4/20 0.43
SMN1; SMN2 Q16637 4/20 0.43
TDP1 Q9NUW8 3/20 0.43
MAPT P10636 2/20 0.43
L3MBTL1 Q9Y468 2/20 0.43
GAA P10253 2/20 0.43
POLB P06746 1/20 0.43
RECQL P46063 1/20 0.43
PKM P14618 2/20 0.40
ATG4B Q9Y4P1 3/20 0.40
MEN1 O00255 2/20 0.40
KMT2A Q03164 2/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL375929 0.83
Nitrogen SCHEMBL28031297 0.80 ALDH1A1 (0.92) ALDH1A1HPGDALOX15NOS1MAPK8
Hydrochloric Acid SCHEMBL30272890 0.80 ALDH1A1 (0.92) ALDH1A1HPGDALOX15NOS1MAPK8
Sulfuric Acid SCHEMBL11093353 0.76 ALDH1A1 (0.82) ALDH1A1HPGDALOX15MAPK8MAPK9
SCHEMBL361464 0.72
Hydrochloric Acid SCHEMBL844054 0.70
Bromide SCHEMBL2015236 0.70
SCHEMBL26114001 0.70
SCHEMBL8266427 0.69
Pyrazole SCHEMBL28104011 0.69 ALDH1A1 (0.68) ALDH1A1HPGDALOX15MAPK8MAPK9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4313872-A MONDAZO AND DISAZO DYES CASSELLA AKTIENGESELLSCHAFT (DE) 1982-02-02 US disclosed