Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | PPARD | Q03181 | 2/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | MMP1 | P03956 | 1/20 | 0.30 |
| ▸ | MMP2 | P08253 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11221537 | 0.92 | TSHR (0.41) | TSHRPPARDTP53TDP1MAPT | |
| SCHEMBL1592913 | 0.80 | PPARD (0.50) | TSHRPPARDTP53TDP1MAPT | |
| SCHEMBL4990894 | 0.77 | TSHR (0.46) | TSHRPPARDTP53TDP1MEN1 | |
| SCHEMBL9181802 | 0.76 | ENPP2 (0.40) | TSHRPPARD | |
| SCHEMBL7892388 | 0.72 | TSHR (0.38) | TSHRPPARD | |
| SCHEMBL7899566 | 0.72 | TSHR (0.38) | TSHRPPARD | |
| SCHEMBL7892169 | 0.72 | TSHR (0.38) | TSHRPPARD | |
| SCHEMBL7899920 | 0.72 | TSHR (0.38) | TSHRPPARD | |
| SCHEMBL27496366 | 0.72 | TSHR (0.41) | TSHRPPARDTP53TDP1 | |
| SCHEMBL21925055 | 0.71 | TSHR (0.50) | TSHRPPARDTP53TDP1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4325727-A | Plant growth regulant phosphonoacetals | YEDA RESEARCH AND DEVELOPMENT COMPANY, LTD. (IL) | 1982-04-20 | — | — | US | disclosed |