Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | ENPP2 | Q13822 | 7/20 | 0.37 |
| ▸ | LPAR2 | Q9HBW0 | 3/20 | 0.37 |
| ▸ | PPARD | Q03181 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7892388 | 1.00 | TSHR (0.38) | TSHRENPP2LPAR2PPARD | |
| SCHEMBL7892169 | 1.00 | TSHR (0.38) | TSHRENPP2LPAR2PPARD | |
| SCHEMBL7899917 | 1.00 | TSHR (0.38) | TSHRENPP2LPAR2PPARD | |
| SCHEMBL7899920 | 1.00 | TSHR (0.38) | TSHRENPP2LPAR2PPARD | |
| SCHEMBL9181802 | 0.84 | ENPP2 (0.40) | TSHRENPP2LPAR2PPARD | |
| SCHEMBL4990894 | 0.77 | TSHR (0.46) | TSHRENPP2LPAR2PPARD | |
| SCHEMBL11213634 | 0.72 | TSHR (0.44) | TSHRPPARD | |
| SCHEMBL10429188 | 0.71 | TSHR (0.60) | TSHRENPP2LPAR2PPARD | |
| SCHEMBL11221537 | 0.69 | TSHR (0.41) | TSHRPPARD | |
| SCHEMBL11663356 | 0.66 | ALDH1A1 (0.55) | ENPP2LPAR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6194576-B1 | COUPLING PURINE OR PYRIMIDINE BASE WITH NUCLEOTIDE ANALOG PHOSPHONATE COMPOUND | BIOCHEM PHARMA, INC. (CA) | 2001-02-27 | — | — | US | disclosed |
| US-6127540-A | NUCLEOTIDE ANALOGS MADE BY COUPLING A PURINE OR PYRIMIDINE NUCLEOTIDE BASE OR ANALOGUE THEREOF WITH A 2-(PHOSPHONATE)FURAN OR 2-(PHOSPHONATE)THIOFURAN OF GIVEN FORMULA; USE AS NON-TOXIC ANTIVIRAL DRUGS | BIOCHEM PHARMA, INC. (CA) | 2000-10-03 | — | — | US | disclosed |
| US-6005107-A | Antiviral compounds | BIOCHEM PHARMA, INC. (CA) | 1999-12-21 | — | — | US | disclosed |
| US-5955610-A | COUPLING PHOSPHONATE INTERMEDIATE WITH PURINE OR PYRIMIDINE NUCLEOTIDE BASE | BIOCHEM PHARMA, INC. (CA) | 1999-09-21 | — | — | US | disclosed |
| US-5789394-A | VIRICIDES FOR CYTOMEGALOVIRUS USING NUCLEOTIDES | NGUYEN-BA NGHE (CA) | 1998-08-04 | — | — | US | disclosed |