Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 3/20 | 0.35 |
| ▸ | CA2 | P00918 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | MMP8 | P22894 | 2/20 | 0.31 |
| ▸ | MMP3 | P08254 | 1/20 | 0.31 |
| ▸ | SMYD3 | Q9H7B4 | 2/20 | 0.31 |
| ▸ | THRB | P10828 | 2/20 | 0.30 |
| ▸ | FKBP1A | P62942 | 1/20 | 0.30 |
| ▸ | HTR6 | P50406 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6897802 | 0.73 | FAAH (0.40) | FAAHCA2ALDH1A1MAPTMMP8 | |
| SCHEMBL6904571 | 0.71 | FAAH (0.35) | FAAHCA2ALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL6901404 | 0.69 | FAAH (0.36) | FAAHCA2ALDH1A1MAPTMMP8 | |
| SCHEMBL10722736 | 0.69 | FAAH (0.48) | FAAHCA2ALDH1A1THRB | |
| SCHEMBL7122564 | 0.69 | FAAH (0.48) | FAAHCA2ALDH1A1THRB | |
| SCHEMBL10721831 | 0.69 | FAAH (0.48) | FAAHCA2ALDH1A1THRB | |
| SCHEMBL6897175 | 0.68 | FAAH (0.35) | FAAHCA2ALDH1A1MAPTMMP8 | |
| SCHEMBL6901401 | 0.67 | FAAH (0.41) | FAAHCA2ALDH1A1MAPT | |
| SCHEMBL6897804 | 0.67 | FAAH (0.41) | FAAHCA2ALDH1A1MAPTTHRB | |
| SCHEMBL1069645 | 0.67 | FAAH (0.41) | FAAHCA2ALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0048372-B1 | PROCESS FOR PREPARING PYRAZOLE | BAYER AG (DE) | 1983-10-26 | — | — | EP | disclosed |
| EP-0048372-A2 | Process for preparing pyrazole | BAYER AG (DE) | 1982-03-31 | — | — | EP | disclosed |