Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KLK5 | Q9Y337 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | CCKBR | P32239 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | MAPKAPK2 | P49137 | 1/20 | 0.38 |
| ▸ | RPS6KA1 | Q15418 | 1/20 | 0.38 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.38 |
| ▸ | CSNK1G1 | Q9HCP0 | 1/20 | 0.38 |
| ▸ | ROCK2 | O75116 | 3/20 | 0.37 |
| ▸ | ROCK1 | Q13464 | 2/20 | 0.37 |
| ▸ | TACR3 | P29371 | 1/20 | 0.36 |
| ▸ | GFER | P55789 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11218597 | 0.92 | MEN1 (0.52) | KLK5KMT2AMEN1CCKBRLMNA | |
| SCHEMBL11773759 | 0.90 | MEN1 (0.47) | KLK5KMT2AMEN1CCKBRLMNA | |
| SCHEMBL11214162 | 0.87 | KMT2A (0.46) | KLK5KMT2AMEN1CCKBRLMNA | |
| SCHEMBL10564270 | 0.81 | MEN1 (0.53) | KMT2AMEN1CCKBRLMNAGAA | |
| SCHEMBL10674145 | 0.81 | MEN1 (0.53) | KMT2AMEN1CCKBRLMNAGAA | |
| SCHEMBL11218592 | 0.79 | MEN1 (0.52) | KLK5KMT2AMEN1CCKBRLMNA | |
| SCHEMBL10751872 | 0.79 | MEN1 (0.52) | KMT2AMEN1CCKBRLMNAGAA | |
| SCHEMBL11684599 | 0.79 | KLK5 (0.42) | KLK5KMT2AMEN1CCKBRLMNA | |
| SCHEMBL11688417 | 0.79 | KLK5 (0.42) | KLK5KMT2AMEN1CCKBRLMNA | |
| SCHEMBL11216119 | 0.79 | KMT2A (0.37) | KMT2AMEN1CCKBRLMNAGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4329454-A | Cephalosporin compounds | ELI LILLY AND COMPANY (US) | 1982-05-11 | — | — | US | disclosed |
| US-4144391-A | REPLACING AN ACETOXY GROUP BY A SULFUR NUCLEOPHILE | ELI LILLY AND COMPANY (US) | 1979-03-13 | — | — | US | disclosed |