Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | GAA | P10253 | 2/20 | 0.37 |
| ▸ | GFER | P55789 | 1/20 | 0.37 |
| ▸ | PER2 | O15055 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | CNR1 | P21554 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | TACR3 | P29371 | 1/20 | 0.35 |
| ▸ | GPR88 | Q9GZN0 | 1/20 | 0.35 |
| ▸ | CCKBR | P32239 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | MAPKAPK2 | P49137 | 1/20 | 0.34 |
| ▸ | RPS6KA1 | Q15418 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11212205 | 0.92 | KMT2A (0.38) | KMT2AGAAGFERMEN1LMNA | |
| SCHEMBL11216115 | 0.88 | LMNA (0.39) | KMT2AGAAPER2MEN1LMNA | |
| SCHEMBL11217471 | 0.83 | ALDH1A1 (0.36) | KMT2AGAAGFERMEN1LMNA | |
| SCHEMBL11212202 | 0.80 | MEN1 (0.38) | KMT2AGAAMEN1LMNAALDH1A1 | |
| SCHEMBL11214185 | 0.79 | KLK5 (0.51) | KMT2AGAAGFERMEN1LMNA | |
| SCHEMBL10332386 | 0.78 | KMT2A (0.36) | KMT2AGAAGFERMEN1LMNA | |
| SCHEMBL11733493 | 0.77 | KMT2A (0.41) | KMT2AGAAMEN1LMNAALDH1A1 | |
| SCHEMBL11739896 | 0.77 | KMT2A (0.41) | KMT2AGAAMEN1LMNAALDH1A1 | |
| SCHEMBL11218597 | 0.75 | MEN1 (0.52) | KMT2AGAAMEN1LMNAALDH1A1 | |
| SCHEMBL11732699 | 0.75 | MEN1 (0.41) | KMT2AGAAMEN1LMNAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4329454-A | Cephalosporin compounds | ELI LILLY AND COMPANY (US) | 1982-05-11 | — | — | US | disclosed |
| US-4144391-A | REPLACING AN ACETOXY GROUP BY A SULFUR NUCLEOPHILE | ELI LILLY AND COMPANY (US) | 1979-03-13 | — | — | US | disclosed |