Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA2A | P08913 | 5/20 | 0.76 |
| ▸ | ADRA2B | P18089 | 5/20 | 0.76 |
| ▸ | ADRA2C | P18825 | 5/20 | 0.76 |
| ▸ | ADRA1D | P25100 | 5/20 | 0.76 |
| ▸ | ADRA1A | P35348 | 5/20 | 0.76 |
| ▸ | ADRA1B | P35368 | 5/20 | 0.76 |
| ▸ | DRD2 | P14416 | 2/20 | 0.45 |
| ▸ | DRD1 | P21728 | 1/20 | 0.45 |
| ▸ | FYN | P06241 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL11215555 | 0.98 | ADRA2A (0.74) | ADRA2AADRA2BADRA2CADRA1DADRA1A | |
| SCHEMBL11219951 | 0.81 | ADRA2A (0.73) | ADRA2AADRA2BADRA2CADRA1DADRA1A | |
| Bromide SCHEMBL11216540 | 0.80 | ADRA2A (0.71) | ADRA2AADRA2BADRA2CADRA1DADRA1A | |
| SCHEMBL10921793 | 0.75 | ADRA2A (1.00) | ADRA2AADRA2BADRA2CADRA1DADRA1A | |
| Bromide SCHEMBL9523064 | 0.73 | ADRA2A (0.64) | ADRA2AADRA2BADRA2CADRA1DADRA1A | |
| SCHEMBL9505400 | 0.73 | ADRA2A (0.64) | ADRA2AADRA2BADRA2CADRA1DADRA1A | |
| SCHEMBL9506571 | 0.73 | ADRA2A (0.71) | ADRA2AADRA2BADRA2CADRA1DADRA1A | |
| Bromide SCHEMBL11002465 | 0.73 | ADRA2A (0.76) | ADRA2AADRA2BADRA2CADRA1DADRA1A | |
| Hydrochloric Acid SCHEMBL9503348 | 0.72 | ADRA2A (0.63) | ADRA2AADRA2BADRA2CADRA1DADRA1A | |
| SCHEMBL11213290 | 0.72 | FYN (0.50) | ADRA2AADRA2BADRA2CADRA1DADRA1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0043194-A2 | Bicyclo-octatriene derivatives, pharmaceutical compositions containing them and processes and intermediates for their production | FISONS plc (GB) | 1982-01-06 | — | — | EP | claimed |