Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA2A | P08913 | 5/20 | 0.73 |
| ▸ | ADRA2B | P18089 | 5/20 | 0.73 |
| ▸ | ADRA2C | P18825 | 5/20 | 0.73 |
| ▸ | ADRA1D | P25100 | 5/20 | 0.73 |
| ▸ | ADRA1A | P35348 | 5/20 | 0.73 |
| ▸ | ADRA1B | P35368 | 5/20 | 0.73 |
| ▸ | DRD1 | P21728 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bromide SCHEMBL11216540 | 0.98 | ADRA2A (0.71) | ADRA2AADRA2BADRA2CADRA1DADRA1A | |
| SCHEMBL11006316 | 0.85 | ADRA2A (1.00) | ADRA2AADRA2BADRA2CADRA1DADRA1A | |
| Bromide SCHEMBL11005474 | 0.83 | ADRA2A (0.97) | ADRA2AADRA2BADRA2CADRA1DADRA1A | |
| SCHEMBL11214217 | 0.81 | ADRA2A (0.76) | ADRA2AADRA2BADRA2CADRA1DADRA1A | |
| Hydrochloric Acid SCHEMBL11215555 | 0.80 | ADRA2A (0.74) | ADRA2AADRA2BADRA2CADRA1DADRA1A | |
| SCHEMBL7445741 | 0.72 | DRD1 (0.72) | ADRA2AADRA2BADRA2CADRA1DADRA1A | |
| SCHEMBL10920901 | 0.72 | ADRA2A (1.00) | ADRA2AADRA2BADRA2CADRA1DADRA1A | |
| SCHEMBL29597291 | 0.72 | ADRA2A (1.00) | ADRA2AADRA2BADRA2CADRA1DADRA1A | |
| SCHEMBL7451520 | 0.70 | DRD1 (0.71) | ADRA2AADRA2BADRA2CADRA1DADRA1A | |
| SCHEMBL8829179 | 0.70 | DRD1 (0.71) | ADRA2AADRA2BADRA2CADRA1DADRA1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0043194-A2 | Bicyclo-octatriene derivatives, pharmaceutical compositions containing them and processes and intermediates for their production | FISONS plc (GB) | 1982-01-06 | — | — | EP | claimed |