Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 4/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | CXCR3 | P49682 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | DNMT3A | Q9Y6K1 | 1/20 | 0.43 |
| ▸ | MCHR1 | Q99705 | 2/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.41 |
| ▸ | HTR2A | P28223 | 1/20 | 0.41 |
| ▸ | TNKS | O95271 | 1/20 | 0.41 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11191065 | 0.89 | MAPT (0.54) | LMNAMAPK1MAPTPOLBHPGD | |
| SCHEMBL11193056 | 0.88 | MAPT (0.46) | LMNAMAPK1MAPTPOLBHPGD | |
| SCHEMBL11182439 | 0.87 | LMNA (0.48) | LMNAMAPK1MAPTPOLBHPGD | |
| SCHEMBL11199855 | 0.87 | DNMT3A (0.48) | LMNAMAPK1MAPTPOLBHPGD | |
| SCHEMBL11441498 | 0.86 | MCHR1 (0.56) | LMNAMAPTPOLBCXCR3DNMT3A | |
| SCHEMBL11165965 | 0.85 | MCHR1 (0.55) | LMNAMAPTPOLBCXCR3MCHR1 | |
| SCHEMBL10356773 | 0.85 | MCHR1 (0.55) | LMNAMAPTPOLBCXCR3MCHR1 | |
| SCHEMBL11165531 | 0.85 | MCHR1 (0.55) | LMNAMAPTPOLBCXCR3MCHR1 | |
| SCHEMBL11178554 | 0.85 | MAPT (0.52) | LMNAMAPK1MAPTPOLBCXCR3 | |
| SCHEMBL11201219 | 0.83 | MAPT (0.48) | LMNAMAPTPOLBDNMT3AMCHR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0023569-B1 | DERIVATIVES OF CARBOXYLIC ACIDS, THEIR PREPARATION AND MEDICAMENTS CONTAINING THEM | Dr. Karl Thomae GmbH (DE) | 1983-06-22 | — | — | EP | disclosed |
| EP-0023569-A1 | Derivatives of carboxylic acids, their preparation and medicaments containing them | Dr. Karl Thomae GmbH (DE) | 1981-02-11 | — | — | EP | disclosed |