Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 1/20 | 0.40 |
| ▸ | S1PR3 | Q99500 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5899762 | 0.80 | ARG1 (0.34) | ALOX5ALDH1A1 | |
| SCHEMBL6277470 | 0.78 | ARG1 (0.38) | — | |
| SCHEMBL6799921 | 0.78 | GRM2 (0.33) | — | |
| SCHEMBL5560856 | 0.78 | GRM2 (0.33) | — | |
| SCHEMBL17165739 | 0.75 | GRM2 (0.31) | — | |
| SCHEMBL11136787 | 0.74 | GRM2 (0.53) | — | |
| SCHEMBL26695374 | 0.74 | ALOX5 (0.43) | ALOX5S1PR3ALDH1A1 | |
| SCHEMBL8240798 | 0.73 | GRM2 (0.52) | ALOX5 | |
| SCHEMBL8244081 | 0.73 | GRM2 (0.52) | ALOX5 | |
| SCHEMBL28874035 | 0.73 | GRM2 (0.52) | ALOX5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0015604-B1 | COMPOUNDS AND COMPOSITIONS FOR USE IN INHIBITION OF LIPOGENESIS IN MAMMALS | SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) | 1983-02-23 | — | — | EP | claimed |
| EP-0015604-B1 | COMPOUNDS AND COMPOSITIONS FOR USE IN INHIBITION OF LIPOGENESIS IN MAMMALS | SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) | 1983-02-23 | — | — | EP | disclosed |