Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA1 | P14867 | 2/20 | 0.33 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.33 |
| ▸ | HTR1A | P08908 | 1/20 | 0.33 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.33 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11206145 | 0.82 | TAAR1 (0.36) | GABRA1GABRB2HTR1ATAAR1 | |
| SCHEMBL11211231 | 0.80 | TAAR1 (0.37) | GABRA1GABRB2HTR1ATAAR1 | |
| SCHEMBL9309998 | 0.78 | RAF1 (0.36) | — | |
| SCHEMBL9309994 | 0.78 | RAF1 (0.36) | — | |
| SCHEMBL11208533 | 0.76 | TAAR1 (0.34) | HTR1ATAAR1 | |
| SCHEMBL11204854 | 0.75 | MAPT (0.49) | — | |
| SCHEMBL11213582 | 0.75 | KCNH2 (0.49) | — | |
| SCHEMBL11210758 | 0.75 | MAOB (0.32) | — | |
| SCHEMBL11210840 | 0.74 | CYP1A1 (0.45) | — | |
| SCHEMBL11210877 | 0.70 | PTGER1 (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0034474-B1 | SUBSTITUTED IMIDAZOLES, THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THE SAME | Farmos-Yhtyma Oy (FI) | 1983-01-26 | — | — | EP | disclosed |
| US-4333947-A | HYPOTENSIVE AGENTS, BACTERICIDES, FUNGICIDES | FARMOS-YHTYMA OY (FI) | 1982-06-08 | — | — | US | disclosed |
| EP-0034474-A1 | Substituted imidazoles, their preparation and pharmaceutical compositions containing the same | Farmos-Yhtyma Oy (FI) | 1981-08-26 | — | — | EP | disclosed |