Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAF1 | P04049 | 2/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.32 |
| ▸ | PARP1 | P09874 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9309998 | 1.00 | RAF1 (0.36) | RAF1KCNH2PARP1 | |
| SCHEMBL11208885 | 0.82 | PARP1 (0.34) | PARP1 | |
| SCHEMBL11206134 | 0.81 | RAB9A (0.33) | — | |
| SCHEMBL11213582 | 0.79 | KCNH2 (0.49) | KCNH2PARP1 | |
| SCHEMBL11210758 | 0.79 | MAOB (0.32) | — | |
| SCHEMBL11204854 | 0.79 | MAPT (0.49) | RAF1KCNH2 | |
| SCHEMBL11214569 | 0.78 | GABRA1 (0.33) | — | |
| SCHEMBL11210840 | 0.78 | CYP1A1 (0.45) | — | |
| SCHEMBL10744133 | 0.77 | ACP1 (0.35) | PARP1 | |
| SCHEMBL11206110 | 0.74 | TAAR1 (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0437030-A2 | 4-Substituted imidazoles for lowering intraocular pressure | ORION-YHTYMÀ OY (FI) | 1991-07-17 | — | — | EP | claimed |
| US-5304569-A | Compositions and their use in lowering intraocular pressure | ORION-YHTYMA OY (FI) | 1994-04-19 | — | — | US | disclosed |
| EP-0437030-A2 | 4-Substituted imidazoles for lowering intraocular pressure | ORION-YHTYMÀ OY (FI) | 1991-07-17 | — | — | EP | disclosed |