Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.36 |
| ▸ | HTR1A | P08908 | 1/20 | 0.36 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.30 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11214569 | 0.82 | GABRA1 (0.33) | TAAR1HTR1AGABRA1GABRB2 | |
| SCHEMBL11211231 | 0.81 | TAAR1 (0.37) | TAAR1HTR1AGABRA1GABRB2 | |
| SCHEMBL11208533 | 0.80 | TAAR1 (0.34) | TAAR1HTR1A | |
| SCHEMBL5528070 | 0.74 | GABRA1 (0.40) | TAAR1HTR1AGABRA1GABRB2 | |
| SCHEMBL11208205 | 0.74 | HDAC4 (0.37) | — | |
| SCHEMBL11206134 | 0.73 | RAB9A (0.33) | — | |
| SCHEMBL29952858 | 0.72 | KMT2A (0.45) | — | |
| SCHEMBL2559134 | 0.72 | KMT2A (0.45) | — | |
| SCHEMBL2559133 | 0.72 | KMT2A (0.45) | — | |
| SCHEMBL11215662 | 0.71 | GABRA1 (0.40) | TAAR1HTR1AGABRA1GABRB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0034474-B1 | SUBSTITUTED IMIDAZOLES, THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THE SAME | Farmos-Yhtyma Oy (FI) | 1983-01-26 | — | — | EP | disclosed |
| US-4333947-A | HYPOTENSIVE AGENTS, BACTERICIDES, FUNGICIDES | FARMOS-YHTYMA OY (FI) | 1982-06-08 | — | — | US | disclosed |