SCHEMBL11214731

SCHEMBL11214731

Cc1cc(O)c(Br)c(Br)c1O

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PTPN1 P18031 3/20 0.46
CA1 P00915 4/20 0.43
CA2 P00918 4/20 0.43
KDM4E B2RXH2 4/20 0.43
MAPT P10636 4/20 0.43
MEN1 O00255 2/20 0.43
KMT2A Q03164 2/20 0.43
LMNA P02545 2/20 0.43
USP2 O75604 1/20 0.43
HTT P42858 1/20 0.43
ALDH1A1 P00352 5/20 0.40
HPGD P15428 3/20 0.40
ALOX15 P16050 3/20 0.40
MAPK1 P28482 3/20 0.40
HIF1A Q16665 3/20 0.40
RECQL P46063 2/20 0.40
HSD17B10 Q99714 2/20 0.40
CYP3A4 P08684 2/20 0.40
CYP1A2 P05177 1/20 0.40
CYP2D6 P10635 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL86951 0.82 CA1 (0.42) PTPN1CA1CA2KDM4EMAPT
SCHEMBL6027776 0.82 CA1 (0.42) PTPN1CA1CA2KDM4EMAPT
SCHEMBL28498020 0.81 PTPN1 (0.43) PTPN1CA1CA2KDM4EMAPT
SCHEMBL28278921 0.79 PTPN1 (0.52) PTPN1CA1CA2KDM4EMAPT
SCHEMBL14283727 0.78 CYP3A4 (0.41) PTPN1CA1CA2KDM4EMAPT
SCHEMBL31088765 0.74 ALDH1A1 (0.40) PTPN1CA1CA2KDM4EMAPT
SCHEMBL13296156 0.74 CA1 (0.46) PTPN1CA1CA2KDM4EMAPT
SCHEMBL7173958 0.74 ALDH1A1 (0.40) PTPN1CA1CA2KDM4EMAPT
SCHEMBL28781951 0.74 SELL (0.43) PTPN1CA1CA2KDM4EMAPT
SCHEMBL68947 0.72 PTPN1 (0.54) PTPN1CA1CA2ALDH1A1HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-57021332-A None JP disclosed
JP-S5721332-A HYDROQUINONE DERIVATIVE AND ITS PREPARATION MITSUI PETROCHEM IND LTD 1982-02-04 JP disclosed