SCHEMBL86951

SCHEMBL86951

Cc1cc(O)c(Br)c(C)c1O

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA1 P00915 2/20 0.42
CA2 P00918 2/20 0.42
MAPT P10636 7/20 0.41
KDM4E B2RXH2 5/20 0.41
MEN1 O00255 3/20 0.41
KMT2A Q03164 3/20 0.41
LMNA P02545 3/20 0.41
HTT P42858 2/20 0.41
USP2 O75604 1/20 0.41
ALDH1A1 P00352 8/20 0.39
HPGD P15428 5/20 0.39
RECQL P46063 2/20 0.39
CYP3A4 P08684 4/20 0.39
ALOX15 P16050 3/20 0.39
HIF1A Q16665 3/20 0.39
ALOX12 P18054 3/20 0.39
MAPK1 P28482 3/20 0.39
CYP1A2 P05177 2/20 0.39
CYP2D6 P10635 2/20 0.39
CYP2C9 P11712 2/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31088765 0.82 ALDH1A1 (0.40) CA1CA2MAPTKDM4EMEN1
SCHEMBL29768668 0.82 CA1 (0.43) CA1CA2MAPTKDM4EMEN1
SCHEMBL9683862 0.82 CA1 (0.43) CA1CA2MAPTKDM4EMEN1
SCHEMBL11214731 0.82 PTPN1 (0.46) CA1CA2MAPTKDM4EMEN1
SCHEMBL7173958 0.82 ALDH1A1 (0.40) CA1CA2MAPTKDM4EMEN1
SCHEMBL6027776 0.80 CA1 (0.42) CA1CA2MAPTKDM4EMEN1
SCHEMBL11820209 0.80 CA1 (0.42) CA1CA2MAPTKDM4EMEN1
SCHEMBL6433514 0.80 CA1 (0.44) CA1CA2MAPTKDM4EMEN1
SCHEMBL25581857 0.78 ACHE (0.43) CA1CA2MAPTKDM4EMEN1
SCHEMBL9503616 0.78 MAPT (0.36) CA1CA2MAPTKDM4EMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2479203-A1 AROMATIC POLYESTER Muroran Institute of Technology (JP) 2012-07-25 EP disclosed
US-20120172570-A1 AROMATIC POLYESTER NITTA CORPORATION 2012-07-05 US disclosed
US-8129493-B2 Aromatic polyester MURORAN INSTITUTE OF TECHNOLOGY (JP) 2012-03-06 US disclosed
US-20110224343-A1 MODIFIER FOR AROMATIC POLYESTER AND AROMATIC POLYESTER RESIN COMPOSITION COMPRISING THE SAME MURORAN INSTITUTE OF TECHNOLOGY (JP) 2011-09-15 US disclosed
US-20110092662-A1 AROMATIC POLYESTER NITTA CORPORATION (JP) 2011-04-21 US disclosed
US-7038067-B2 Process for synthesizing d-tocotrienols from 2-vinylchromane compound YASOO HEALTH, INC. (US) 2006-05-02 US disclosed
US-20050124687-A1 Process for synthesizing d-tocotrienols COULADOUROS ELIAS A (GR) 2005-06-09 US disclosed
US-20050124688-A1 Process for synthesizing d-tocotrienols from 2-vinylchromane compound YASOO HEALTH, INC. 2005-06-09 US disclosed
WO-2005035491-A2 PROCESS FOR SYNTHESIZING d-TOCOTRIENOLS FROM 2- VINYLCHROMANE COMPOUND YASOO HEALTH, INC. (US) 2005-04-21 WO disclosed
WO-2005035490-A2 PROCESS FOR SYNTHESIZING d-TOCOTRIENOLS YASOO HEALTH, INC. (US) 2005-04-21 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110224343-A1 MODIFIER FOR AROMATIC POLYESTER AND AROMATIC POLYESTER RESIN COMPOSITION COMPRISING THE SAME F12, PHAX, WDR82 CA1 550/4885CA2 612/4885MAPT 1923/4885
US-20050124688-A1 Process for synthesizing d-tocotrienols from 2-vinylchromane compound FDFT1, DHCR7, DDT CA1 3703/4885CA2 4376/4885MAPT 4809/4885
US-20050124687-A1 Process for synthesizing d-tocotrienols UGT8, DDOST, GGPS1 CA1 4581/4885CA2 4668/4885MAPT 4791/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.