Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.56 |
| ▸ | AOC3 | Q16853 | 2/20 | 0.52 |
| ▸ | LMNA | P02545 | 2/20 | 0.52 |
| ▸ | CNR2 | P34972 | 1/20 | 0.52 |
| ▸ | TP53 | P04637 | 1/20 | 0.50 |
| ▸ | MGLL | Q99685 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.45 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.45 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.45 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.45 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.45 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.45 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.45 |
| ▸ | PRMT8 | Q9NR22 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.45 |
| ▸ | HTR1A | P08908 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Fluoride SCHEMBL8376221 | 0.90 | TSHR (0.54) | TSHRALDH1A1AOC3LMNACNR2 | |
| SCHEMBL5271843 | 0.88 | TSHR (0.56) | TSHRALDH1A1AOC3LMNACNR2 | |
| SCHEMBL3271148 | 0.83 | TSHR (0.60) | TSHRALDH1A1AOC3LMNATP53 | |
| SCHEMBL7882263 | 0.83 | AOC3 (0.55) | TSHRALDH1A1AOC3LMNACNR2 | |
| SCHEMBL375111 | 0.79 | KDM4E (0.68) | TSHRALDH1A1AOC3LMNACNR2 | |
| SCHEMBL81248 | 0.79 | HRH3 (0.65) | TSHRALDH1A1AOC3LMNACNR2 | |
| SCHEMBL28072533 | 0.78 | CARM1 (0.50) | TSHRALDH1A1AOC3KDM4ESLC6A2 | |
| SCHEMBL6806665 | 0.78 | LMNA (0.47) | TSHRALDH1A1AOC3LMNACNR2 | |
| Bromide SCHEMBL11663269 | 0.77 | HRH3 (0.62) | TSHRALDH1A1AOC3LMNACNR2 | |
| Iodide SCHEMBL21693881 | 0.77 | HRH3 (0.62) | TSHRALDH1A1AOC3LMNACNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4386053-A | IMPREGNATION OF SUBSTRATE WITH ORGANIC PEROXIDE, CHROMOGEN, BUFFER AND STABILIZER | TERUMO CORPORATION (JP) | 1983-05-31 | — | — | US | disclosed |