Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 3/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | MGLL | Q99685 | 1/20 | 0.44 |
| ▸ | CNR2 | P34972 | 1/20 | 0.43 |
| ▸ | AOC3 | Q16853 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | CA12 | O43570 | 1/20 | 0.40 |
| ▸ | CA9 | Q16790 | 1/20 | 0.40 |
| ▸ | TSPO | P30536 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11214749 | 0.78 | TSHR (0.58) | LMNATSHRALDH1A1MGLLCNR2 | |
| Fluoride SCHEMBL8376221 | 0.74 | TSHR (0.54) | LMNATSHRALDH1A1MGLLCNR2 | |
| SCHEMBL5271843 | 0.72 | TSHR (0.56) | LMNATSHRALDH1A1MGLLCNR2 | |
| SCHEMBL7882263 | 0.72 | AOC3 (0.55) | LMNATSHRALDH1A1CNR2AOC3 | |
| SCHEMBL29983056 | 0.72 | LMNA (0.47) | LMNATSHRALDH1A1MGLLCNR2 | |
| SCHEMBL1280222 | 0.72 | ALDH1A1 (0.48) | LMNATSHRALDH1A1MGLLAOC3 | |
| SCHEMBL1348975 | 0.70 | TSHR (0.54) | LMNATSHRALDH1A1MGLLCNR2 | |
| SCHEMBL81248 | 0.69 | HRH3 (0.65) | LMNATSHRALDH1A1CNR2AOC3 | |
| SCHEMBL375111 | 0.69 | KDM4E (0.68) | LMNATSHRALDH1A1CNR2AOC3 | |
| Hydrochloric Acid SCHEMBL11353607 | 0.68 | TSHR (0.52) | LMNATSHRALDH1A1MGLLCNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040142854-A1 | Compounds and methods for stimulating beta-catenin mediated gene expression and differentiation | ADHEREX TECHNOLOGIES, INC. (CA) | 2004-07-22 | — | — | US | disclosed |
| US-6706685-B1 | Compounds and methods for stimulating β-catenin mediated gene expression and differentiation | ADHEREX TECHNOLOGIES INC. (CA) | 2004-03-16 | — | — | US | disclosed |
| WO-2000059939-A1 | COMPOUNDS AND METHODS FOR STIMULATING β-CATENIN MEDIATED GENE EXPRESSION AND DIFFERENTIATION | ADHEREX TECHNOLOGIES INC. (CA) | 2000-10-12 | — | — | WO | disclosed |