Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXRA | P19793 | 11/20 | 0.45 |
| ▸ | RXRB | P28702 | 3/20 | 0.41 |
| ▸ | CYP26A1 | O43174 | 2/20 | 0.41 |
| ▸ | CYP26B1 | Q9NR63 | 2/20 | 0.41 |
| ▸ | RXRG | P48443 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.35 |
| ▸ | SRD5A2 | P31213 | 2/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | KDM1A | O60341 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9123562 | 0.77 | — | — | |
| SCHEMBL6021972 | 0.71 | AKR1C1 (0.41) | ALDH1A1TSHRPKM | |
| SCHEMBL7576134 | 0.71 | AKR1C1 (0.41) | ALDH1A1TSHRPKM | |
| SCHEMBL9471910 | 0.70 | RXRA (0.56) | RXRAALDH1A1TP53TSHRSRD5A2 | |
| SCHEMBL11400568 | 0.69 | TSHR (0.46) | RXRARXRBCYP26A1CYP26B1ALDH1A1 | |
| SCHEMBL7894906 | 0.69 | AKR1C1 (0.39) | ALDH1A1TSHRPOLBGAAPKM | |
| SCHEMBL11894644 | 0.69 | TSHR (0.50) | RXRAALDH1A1TP53TSHRSRD5A2 | |
| SCHEMBL900808 | 0.69 | ESR1 (0.57) | RXRAALDH1A1TP53TSHRSRD5A2 | |
| SCHEMBL9472582 | 0.69 | ESR1 (0.57) | RXRAALDH1A1TP53TSHRSRD5A2 | |
| SCHEMBL11382551 | 0.68 | TP53 (0.44) | RXRARXRBCYP26A1CYP26B1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-57002241-A | — | — | None | — | — | JP | disclosed |
| JP-S572241-A | PREPARATION OF DIESTER TYPE LIQUID CRYSTAL | HITACHI LTD | 1982-01-07 | — | — | JP | disclosed |