SCHEMBL900808

SCHEMBL900808

O=C(O)c1ccc(C2(c3ccc(C(=O)O)cc3)CCCCC2)cc1

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ESR1 P03372 3/20 0.57
ESR2 Q92731 3/20 0.57
RXRA P19793 3/20 0.54
ALDH1A1 P00352 4/20 0.52
L3MBTL1 Q9Y468 1/20 0.52
TSHR P16473 3/20 0.50
ADORA3 P0DMS8 1/20 0.50
TP53 P04637 1/20 0.50
HSD11B1 P28845 1/20 0.45
SRD5A2 P31213 2/20 0.44
CA1 P00915 2/20 0.43
CA2 P00918 2/20 0.43
CA12 O43570 1/20 0.43
CA3 P07451 1/20 0.43
TYR P14679 1/20 0.43
DRD1 P21728 1/20 0.43
CA4 P22748 1/20 0.43
CA6 P23280 1/20 0.43
CA5A P35218 1/20 0.43
CA7 P43166 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9472582 1.00 ESR1 (0.57) ESR1ESR2RXRAALDH1A1L3MBTL1
SCHEMBL9471910 0.98 RXRA (0.56) ESR1ESR2RXRAALDH1A1L3MBTL1
SCHEMBL11990115 0.91 ALOX15 (0.59) ESR1ESR2RXRAALDH1A1L3MBTL1
SCHEMBL17503456 0.89 RXRA (0.64) ESR1ESR2RXRAALDH1A1TSHR
SCHEMBL12918483 0.87 CA1 (0.62) RXRAALDH1A1ADORA3CA1CA2
SCHEMBL8439272 0.83 RXRA (0.58) RXRATSHRTP53SRD5A2CA1
SCHEMBL12918485 0.83 ADORA3 (0.58) RXRAALDH1A1L3MBTL1TSHRADORA3
SCHEMBL2357529 0.82 TSHR (0.48) RXRAALDH1A1TSHRTP53SRD5A2
SCHEMBL9472249 0.82 ESR1 (0.55) ESR1ESR2RXRAALDH1A1L3MBTL1
SCHEMBL9472246 0.82 ESR1 (0.55) ESR1ESR2RXRAALDH1A1L3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 94 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5342904-A Polymer modified adducts of epoxy resins and active hydrogen containing compounds containing mesogenic moieties THE DOW CHEMICAL COMPANY (US) 1994-08-30 US claimed
US-5235008-A Curable THE DOW CHEMICAL COMPANY (US) 1993-08-10 US claimed
US-5183926-A Process for the preparation of aromatic dicarboxylic acids and aromatic hydrocarbons BAYER AKTIENGESELLSCHAFT (DE) 1993-02-02 US claimed
EP-4636041-A1 COMPOSITE POLYMER MATERIAL, METHOD FOR PRODUCING SAME, AND OPTICAL MATERIAL The University of Osaka (JP) 2025-10-22 EP disclosed
US-20240327578-A1 SILICONE-BASED POLYMER COMPOUND AND SILICONE-BASED POLYMER MATERIAL OSAKA UNIVERSITY (JP) 2024-10-03 US disclosed
US-12054571-B2 Host-group-containing polymerizable monomer, polymer material, method for producing same, and clathrate compound and method for producing same OSAKA UNIVERSITY (JP) 2024-08-06 US disclosed
WO-2024128306-A1 COMPOSITE POLYMER MATERIAL, METHOD FOR PRODUCING SAME, AND OPTICAL MATERIAL 国立大学法人大阪大学 2024-06-20 WO disclosed
EP-4375312-A1 SILICONE-BASED POLYMER COMPOUND AND SILICONE-BASED POLYMER MATERIAL OSAKA UNIVERSITY (JP) 2024-05-29 EP disclosed
US-11866584-B2 High-refractive-index composition, high-refractive-index film, and method for manufacturing high-refractive-index film LG CHEM, LTD. (KR) 2024-01-09 US disclosed
US-20230192931-A1 HOST-GROUP-CONTAINING POLYMERIZABLE MONOMER, POLYMER MATERIAL, METHOD FOR PRODUCING SAME, AND CLATHRATE COMPOUND AND METHOD FOR PRODUCING SAME OSAKA UNIVERSITY (JP) 2023-06-22 US disclosed
CN-111801355-B Polymer material and method for producing same 国立大学法人大阪大学 2023-02-28 CN disclosed
US-5276184-A Curing agents for epoxy resins for thermosetting resins THE DOW CHEMICAL COMPANY (US) 1994-01-04 US disclosed
US-5241021-A Reacting isocyanate with alkoxylated epoxy resin adducts and one or more compounds having active hydrogens; blowing agents THE DOW CHEMICAL COMPANY (US) 1993-08-31 US disclosed
US-5235008-A Curable THE DOW CHEMICAL COMPANY (US) 1993-08-10 US disclosed
US-5183926-A Process for the preparation of aromatic dicarboxylic acids and aromatic hydrocarbons BAYER AKTIENGESELLSCHAFT (DE) 1993-02-02 US disclosed
US-5110895-A Lenses, protective coatings, stabilizers of ultraviolet light BAYER AKTIENGESELLSCHAFT (DE) 1992-05-05 US disclosed
EP-0478918-A2 Adducts of epoxy resins and active hydrogen containing compounds containing mesogenic moieties THE DOW CHEMICAL COMPANY (US) 1992-04-08 EP disclosed
EP-0469492-A2 Polymer modified adducts of epoxy resins and active hydrogen containing compounds containing mesogenic moieties THE DOW CHEMICAL COMPANY (US) 1992-02-05 EP disclosed
EP-0414066-A2 Polyesters and polyestercarbonates BAYER AG (DE) 1991-02-27 EP disclosed
EP-0414062-A2 Process for preparing aromatic dicarboxylic acids and novel aromatic dicarboxylic acids BAYER AG (DE) 1991-02-27 EP disclosed