SCHEMBL11214943

SCHEMBL11214943

CCC(C)OC(C(=O)OCc1cccc(Oc2ccccc2)c1)C(C)C

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MMP1 P03956 2/20 0.47
MMP2 P08253 1/20 0.46
MMP9 P14780 1/20 0.46
MMP12 P39900 1/20 0.46
CETP P11597 1/20 0.46
PTGES O14684 1/20 0.46
FFAR1 O14842 8/20 0.45
TDP1 Q9NUW8 2/20 0.45
MME P08473 1/20 0.45
ACE P12821 1/20 0.45
CPA1 P15085 1/20 0.45
ACE2 Q9BYF1 1/20 0.45
LMNA P02545 1/20 0.45
ADRA2A P08913 1/20 0.45
CNR1 P21554 1/20 0.45
ATM Q13315 1/20 0.45
L3MBTL1 Q9Y468 1/20 0.45
FFAR4 Q5NUL3 2/20 0.44
PTGS1 P23219 1/20 0.42
TSHR P16473 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11714224 0.85 PPARG (0.51) MMP1MMP2MMP9MMP12CETP
SCHEMBL11710031 0.82 MMP1 (0.49) MMP1MMP2MMP9MMP12CETP
SCHEMBL11710920 0.81 FFAR1 (0.53) MMP1MMP2MMP9MMP12CETP
SCHEMBL11711732 0.81 FFAR1 (0.54) MMP1MMP2MMP9MMP12CETP
SCHEMBL11715157 0.81 FFAR1 (0.54) MMP1MMP2MMP9MMP12CETP
SCHEMBL11719256 0.81 SMN1; SMN2 (0.50) MMP1MMP2MMP9MMP12CETP
SCHEMBL11719290 0.81 MTNR1B (0.48) MMP1MMP2MMP9MMP12PTGES
SCHEMBL10795614 0.81 MMP1 (0.54) MMP1MMP2MMP9MMP12CETP
SCHEMBL22066497 0.81 MMP1 (0.56) MMP1MMP2MMP9MMP12CETP
SCHEMBL11712200 0.80 PPARG (0.61) MMP1MMP2MMP9MMP12PTGES

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-57026602-A None JP disclosed
JP-S5726602-A INSECTICIDE CONTAINING ISOVALERIC ESTER DERIVATIVE DAINIPPON JIYOCHIYUUGIKU KK 1982-02-12 JP disclosed