Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.49 |
| ▸ | HTT | P42858 | 3/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | RECQL | P46063 | 1/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | GLA | P06280 | 2/20 | 0.46 |
| ▸ | PTPRF | P10586 | 1/20 | 0.44 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.44 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.44 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8635097 | 0.83 | MAPT (0.65) | MAPTALDH1A1SMN1; SMN2HTTMEN1 | |
| Ammonia Solution, Strong SCHEMBL6701329 | 0.81 | MAPT (0.62) | MAPTALDH1A1SMN1; SMN2HTTMEN1 | |
| SCHEMBL9820267 | 0.80 | MAPT (0.61) | MAPTALDH1A1SMN1; SMN2HTTMEN1 | |
| SCHEMBL6563884 | 0.80 | MAPT (0.61) | MAPTALDH1A1SMN1; SMN2HTTMEN1 | |
| SCHEMBL30800484 | 0.80 | MAPT (0.61) | MAPTALDH1A1SMN1; SMN2HTTMEN1 | |
| SCHEMBL4616467 | 0.79 | MAPT (0.59) | MAPTALDH1A1SMN1; SMN2HTTMEN1 | |
| SCHEMBL5157176 | 0.76 | MAPT (0.59) | MAPTALDH1A1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL3662904 | 0.76 | MAPT (0.59) | MAPTALDH1A1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL9149907 | 0.75 | ALDH1A1 (0.63) | MAPTALDH1A1SMN1; SMN2HTTMEN1 | |
| SCHEMBL4332876 | 0.75 | MAPT (0.54) | MAPTALDH1A1SMN1; SMN2HTTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0081790-A1 | p-Phenylene diamines, their preparation and use | Henkel Kommanditgesellschaft auf Aktien (DE) | 1983-06-22 | — | — | EP | disclosed |